Myristica fragrans Derived Phytochemicals  against Shikimate Dehydrogenase of E. coli  Causing Diarrhea

Sunanya Das; Debasmita Das; Ashrumochan Nayak; Sonali Dash; Dipankar Bhattacharyay

doi:10.9734/jpri/2020/v32i630502

Research Article Open access CC BY 4.0

Myristica fragrans Derived Phytochemicals against Shikimate Dehydrogenase of E. coli Causing Diarrhea

Sunanya Das, Debasmita Das, Ashrumochan Nayak, Sonali Dash, Dipankar Bhattacharyay

Journal of Pharmaceutical Research International · pp. 110–112 · Published 15 May 2020

10.9734/jpri/2020/v32i630502

Abstract

Medicinal plants play a key role in human health care. Phytochemicals can be derived from different parts of plants. Different medicinal plants and their phytoextracts have shown anti-microbial action. Phytochemicals from Myristica fragrans plant extract are traditionally used to cure Diarrhea. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that Eugenol can effectively deactivate the shikimate dehydrogenase enzyme thereby interrupting the life cycle of the organism.

Phytochemical Myristica fragrans diarrhea enzyme

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Sunanya Das, Debasmita Das, Ashrumochan Nayak, Sonali Dash, Dipankar Bhattacharyay (2020). Myristica fragrans Derived Phytochemicals against Shikimate Dehydrogenase of E. coli Causing Diarrhea. Journal of Pharmaceutical Research International , 110–112. https://doi.org/10.9734/jpri/2020/v32i630502

Affiliations

Sunanya Das — Centurion University of Technology and Management, Odisha, India.
Debasmita Das — Centurion University of Technology and Management, Odisha, India.
Ashrumochan Nayak — Centurion University of Technology and Management, Odisha, India.
Sonali Dash — Centurion University of Technology and Management, Odisha, India.
Dipankar Bhattacharyay — Centurion University of Technology and Management, Odisha, India. and Go to Market Laboratory, Gram Tarang, Odisha, India.

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