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Research Article Open access CC BY 4.0

Modern Solutions in the Treatment of HIV: From Antiretroviral Drug Therapy to Human Genome Editing

Milana Ruslanovna Sebaeva, Iman Vladimirovna Gelogaeva, Naida Ramizovna Suleymanova, Kamila Umarovna Balaeva, Aishat Arslanovna Dauletova, Zuhra Magomedovna Zakoroeva, Saida Hanbertovna Kasheshova, Takis Albertovich Kozmov, Madina Muslimovna Minatulaeva, Alina Yuryevna Maslova

Journal of Pharmaceutical Research International · pp. 159–169 · Published 16 Nov 2021

10.9734/jpri/2021/v33i50A33392

Abstract

The human immunodeficiency virus (HIV) belongs to a group of anthroponotic viral diseases that cause HIV infection in the human body, apotheosely transforming into acquired immunodeficiency syndrome (AIDS). HIV infection, in people without adequate treatment, can lead to serious damage to the immune system (hereinafter referred to as IS), which leads to a sharp decrease in resistance to conditionally pathogenic microbes, as well as to the prevalence of oncological pathologies that may lead to death. Due to its simplicity, convenience, efficiency and cost-effectiveness, CRISPR/Cas has found application in a short period of time in a wide variety of fields of fundamental and applied medicine and biotechnology.

HIV antiretroviral therapy genetic engineering genome editing

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