Medicinal Plants from the Brazilian Savanna with Antibacterial Properties
Ary Fernandes Júnior, Gabriela S. da Silva, Lidiane N. Barbosa, Fernanda C. B. Alves, Bruna F. M. T. Andrade, Mariana Albano, Luiz C. Di Stasi
European Journal of Medicinal Plants · pp. 1–13 · Published 9 Oct 2013
10.9734/EJMP/2014/5945Abstract
Aims: Research on natural antimicrobials has increased due to the emergence of microbial strains resistant to conventional antibiotics. We investigated and report here the in vitro antibacterial properties of crude extracts from Brazilian savanna plants (Achyrocline satureioides (Lam.) DC (“macela”), Stryphnodendron adstringens (Mart.) Coville (”barbatimão”), Miconia rubiginosa (Bonpl.) DC (“quaresma branca”), Davilla elliptica A. St.-Hil. (“lixinha”), Siparuna guianensis (“negramina”) and Solanum lycocarpum A. St.-Hil. (“lobeira”). Place and Duration of Study: Department of Microbiology and Immunology, Biosciences Institute, São Paulo State University from January 2010 to December 2011. Methodology: Antibacterial activities were investigated using two methods: the disk diffusion method against American Type Culture Collection bacterial strains (Staphylococcus aureus – ATCC 25923, Escherichia coli – ATCC 22652, and Pseudomonas aeruginosa – ATCC 27853) and the susceptibility assays by agar dilution method (Mueller Hinton Agar (MHA) aiming the minimal inhibitory concentrations (MIC) and MIC90% (mg.mL-1), against S. aureus, E. coli and P. aeruginosa strains isolated from human clinical specimens. Qualitative phytochemical analysis of crude extracts was also performed. Results: By agar dilution test, the D. elliptica leaf extract was efficient against all strains (MIC90% values of 0.7, 2.6, and 2.1 mg.mL-1 against S. aureus, E. coli, and P. aeruginosa, respectively), while the S. guianensis leaf extract showed the lowest activity (12.2, >32.0, and 26.0 mg.mL-1 against S. aureus, E. coli, and P. aeruginosa, respectively). We detected flavonoids and phenolic compounds in all studied extracts. Conclusion: All studied extracts showed antibacterial activity by the agar dilution method, although M. rubiginosa and S. guianensis leaves extracts did not show inhibitory action against E. coli and P. aeruginosa strains. There was a greater sensitivity of S. aureus and the D.elliptica leaf extract showed the highest efficiency over most of the strains tested. Additionally, the results show that it is possible to obtain conflicting results using the disk diffusion method and the dilution method.
References (29)
- 1 Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically
- 2 Plant Products as Antimicrobial Agents [DOI]
- 3 Plantas medicinais: fatores de influência no conteúdo de metabólitos secundários [DOI]
- 4 Herbal Extracts and Phytochemicals: Plant Secondary Metabolites and the Enhancement of Human Brain function [DOI]
- 5 A brief multi-disciplinary review on antimicrobial resistance in medicine and its linkage to the global environmental microbiota [DOI]
- 6 Synergism between plant extract and antimicrobial drugs used on Staphylococcus aureus diseases [DOI]
- 7 21st Century natural product research and drug development and traditional medicines [DOI]
- 8 Anti-inflammatory activity of alkaloids: a twenty-century review [DOI]
- 9 Gênero Baccharis (Asteraceae): aspectos químicos, econômicos e biológicos [DOI]
- 10 Um panorama atual da química e da farmacologia de naftoquinonas, com ênfase na beta-lapachona e derivados [DOI]
- 11 Diagnóstico Microbiológico. Texto y atlas color.
- 12 Influence of tannins from Stryphnodendron adstringens on growth and virulence factors of Candida albicans [DOI]
- 13 Structures of Steroidal Alkaloid Oligoglycosides, Robeneosides A and B, and Antidiabetogenic Constituents from the Brazilian Medicinal Plant Solanum lycocarpum [DOI]
- 14 Antiprotozoal activity of Brazilian plant extracts from isoquinoline alkaloid-producing families [DOI]
- 15 Antimicrobial macromolecules: synthesis methods and future applications [DOI]
- 16 Antiviral Effect of Guazuma ulmifolia and Stryphnodendron adstringens on Poliovirus and Bovine Herpesvirus [DOI]
- 17 Influence of extracts of Stryphnodendron polyphyllum Mart. and Stryphnodendron obovatum Benth. on the cicatrisation of cutaneous wounds in rats [DOI]
- 18 The use of complex polysaccharides in the management of metabolic diseases: the case of Solanum lycocarpum fruits [DOI]
- 19 Antimicrobial activity and phytochemical analysis of crude extracts and essential oils from medicinal plants [DOI]
- 20 Cytoprotection by Achyrocline satureioides (Lam) D.C. and some of its main flavonoids against oxidative stress [DOI]
- 21 Plantas medicinais usadas para tratamentos dermatológicos, em comunidades da Bacia do Alto Paraguai, Mato Grosso [DOI]
- 22 Effect ofSolanum Glycoalkaloids on Potato Aphid,Macrosiphum euphorbiae [DOI]
- 23 Evaluation of the in vitro antimicrobial activity of crude extracts of three Miconia species [DOI]
- 24 Siparuna guianensis Aublet (negramina): uma revisão [DOI]
- 25 Essential oils from fruits and Leaves ofSiparuna guianensis(Aubl.) Tulasne from Southeastern Brazil [DOI]
- 26 Antimicrobial Activity of Miconia Species (Melastomataceae) [DOI]
- 27 Oxygen active species-scavenger properties of coumarins
- 28 Immunological and microbiological activity of Davilla elliptica St. Hill. (Dilleniaceae) against Mycobacterium tuberculosis [DOI]
- 29 Caracterização farmacognóstica de folhas de Davilla elliptica St.-Hil. (Dilleniaceae) [DOI]
Cited by 14
C. Chin, M. L. Veisaga, H. A. Priestap, T. Commock, K. Campbell, B. Jestrow, J. Francisco-Ortega, M. A. Barbieri · European Journal of Medicinal Plants · 2014
Fernanda C.M. Gallotti, Mairim R. Serafini, Sara M. Thomazzi · Recent Patents on Inflammation & Allergy Drug Discovery · 2021
Rodrigo Trolezi, Juliana Maziero Azanha, Natália Rodrigues Paschoal · Annals of Clinical Microbiology and Antimicrobials · 2017
Showing 3 of 14 known citations — external sources report more than can currently be individually listed.
Related research
- Bacteria Associated with Hospital Handrails in a Tertiary Institution in Nigeria — shares topic coverage
- The Impact of Microorganisms in Pregnancy — shares topic coverage
- Factors Affecting the Use of Probiotics during Antibiotic Therapy — shares topic coverage
- Evaluation of Multi-drug Resistant Bacteria and High Risk of Contamination in Ready to Eat Fruits in Kano Metropolis — shares topic coverage
- Survey and Identification of Bacteria and Fungi Associated with Two Dumpsites in Akure Metropolis — shares topic coverage
Article metrics
Real usage data collected on this platform.
8
Page views
0
PDF downloads
0
Outbound clicks
14
Citations
Views over time
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
Traffic sources
Referring site, by host.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.