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Research Article Open access CC BY 4.0

Extended-Spectrum Beta-Lactamase-Producing Escherichia coli Meningoencephalitis in an Adult: A Case Report

Abdoul Karim Traoré, Hamadé Zonon, Moussa Dao, Ali Soura, Agnihan Viviane Boni

Asian Journal of Research in Infectious Diseases · pp. 59–63 · Published 12 May 2025

10.9734/ajrid/2025/v16i5448

Abstract

Meningoencephalitis caused by Extended-spectrum betalactamase (ESBL)-producing E. coli is rare and associated with a high mortality risk, especially if complicated by septic shock. We report the case of a 28-year-old female patient admitted to intensive care unit with febrile coma and meningeal signs, in whom blood cultures and cerebrospinal fluid cultures identified ESBL-producing E. coli. Despite resuscitation measures and broad-spectrum antibiotic therapy, the outcome was unfavourable. This case highlights the diagnostic and therapeutic challenges of such an infection, as well as the need for documentation.

Meningoencephalitis Escherichia coli ESBL antimicrobial resistance

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