The Rosai-Dorfman Syndrome: A Case Report
Nadia Mebrouk, Najlae Attari, Boutaina Halimi, Loubna Chtouki, Najat Lamalmi, Abdelali Bentahila
Asian Journal of Pediatric Research · pp. 9–12 · Published 20 Apr 2023
10.9734/ajpr/2023/v12i2236Abstract
Sinus histiocytosis, also known as Rosaï Dorfman Syndrome (SRD), is a noncancerous condition that causes the growth of large masses of histiocytes in lymph nodes, primarily in the cervical area. Visceral damage is common, and diagnosis is made through histological examination. The cause of SRD is unknown and can occur at any age, even in children. The condition can sometimes improve spontaneously, but large tumor masses can cause compression and damage, particularly if they involve the retro-orbital or epidural areas. In most cases, it is best to avoid treatment, but therapeutic interventions may be necessary for forms of the disease that pose a direct threat or are progressing. Treatment is not standardized and may involve surgery, corticosteroids, immunosuppressants, and/or alpha interferon, depending on the individual case. We present a case study of a 4-year-old child who had multiple bilateral adenopathies. The diagnosis was verified through a biopsy of the lymph nodes.
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