Hailey-Hailey Disease: A Case Report on a Rare Chronic Blistering Disorder

Abstract

Hailey-Hailey disease (HHD) is a rare autosomal dominant disorder of the skin, marked by recurrent blistering and erosions. Due to its resemblance to other dermatologic conditions, it is often misdiagnosed. A 74-year-old male with a five-year history of recurring skin lesions presented with pus-filled and crusted lesions affecting his limbs, lower back, and chest. He also had a family history of similar skin conditions and was diagnosed with type 2 diabetes mellitus. Histopathological analysis confirmed the diagnosis of HHD. The patient was treated with corticosteroids, tetracycline antibiotics, antihistamines, and diabetes management, with careful monitoring of his blood sugar levels. Following treatment, the patient showed significant improvement. This case underscores the importance of early diagnosis and individualized management, particularly in patients with comorbidities. Further research is needed to refine treatment approaches for HHD.