Skip to content
Research Article Open access CC BY 4.0

Lycopene - A Review: Chemistry, Source, Health Role, Extraction, Applications

Md. Asaduzzaman

Annual Research & Review in Biology · pp. 87–101 · Published 24 Mar 2022

10.9734/arrb/2022/v37i230490

Abstract

Lycopene is an unsaturated carotenoid pigment which is acyclic and open chain, of great dietary prominence obtained mainly from colored plant sources. It is a phytochemical which is found mainly in red amaranth, tomatoes, water melon and other plants and fruits mostly red colored which covered various antioxidant which attracted attentions due to its biological properties. Lycopene has critical role in the prevention of tumor and cancer. Various ways can be utilized to identify, extract and purify lycopene from various sources by efficient analytical support. Several analyses have been attended for the extraction and quantification of lycopene in various natural sources such as various red leaf plants and fruits. This review study highlights lycopene as a carotenoid pigment including auspicious nutraceutical implications, and counts the important plant and also microbial sources for its production, and methods to calculate its bioavailability and utilization.

Lycopene chemistry extraction applications

References (38)

  1. 1 Chemical studies of anthocyanins: A review [DOI]
  2. 2 Techniques for extraction and isolation of natural products: a comprehensive review [DOI]
  3. 3 Carotenoids and human health [DOI]
  4. 4 Structure and properties of carotenoids in relation to function. [DOI]
  5. 5 Acylated anthocyanins from edible sources and their applications in food systems [DOI]
  6. 6 Role of lycopene as antioxidant carotenoid in the prevention of chronic diseases: A review [DOI]
  7. 7 Evaluation of snack foods from barley–tomato pomace blends by extrusion processing [DOI]
  8. 8 Application of a UV–vis detection-HPLC method for a rapid determination of lycopene and β-carotene in vegetables [DOI]
  9. 9 Content and isomeric ratio of lycopene in food and human blood plasma [DOI]
  10. 10 Revealing the Power of the Natural Red Pigment Lycopene [DOI]
  11. 11 Supercritical carbon dioxide extraction of carotenoids, tocopherols and sitosterols from industrial tomato by-products [DOI]
  12. 12 Xanthophyll carotenoids are more bioaccessible from fruits than dark green vegetables [DOI]
  13. 13 Novel modified ultrasonication technique for the extraction of lycopene from tomatoes [DOI]
  14. 14 Preparative separation and purification of lycopene from tomato skins extracts by macroporous adsorption resins [DOI]
  15. 15 Carotenoid Extraction from Plants Using a Novel, Environmentally Friendly Solvent [DOI]
  16. 16 The Effect of Mixing on the Metastable Zone Width and Nucleation Kinetics in the Anti-Solvent Crystallization of Benzoic Acid [DOI]
  17. 17 Concentrations of condensed tannins and anthocyanins in common bean seed coats [DOI]
  18. 18 Tomato Lycopene and Inflammatory Cascade: Basic Interactions and Clinical Implications [DOI]
  19. 19 Ultrasound assisted extraction of lycopene from tomato processing wastes [DOI]
  20. 20 Application of high-speed countercurrent chromatography to the large-scale isolation of anthocyanins [DOI]
  21. 21 Lycopene prevents 7-ketocholesterol-induced oxidative stress, cell cycle arrest and apoptosis in human macrophages [DOI]
  22. 22 Lycopene: Its Properties and Relationship to Human Health [DOI]
  23. 23 Solubility of lycopene in supercritical CO2 fluid as affected by temperature and pressure [DOI]
  24. 24 A Review on Lycopene—Extraction, Purification, Stability and Applications [DOI]
  25. 25 Mixture Approach for Optimizing Lycopene Extraction from Tomato and Tomato Products [DOI]
  26. 26 Plastid and Stromule Morphogenesis in Tomato [DOI]
  27. 27 Separation of polar betalain pigments from cacti fruits of Hylocereus polyrhizus by ion-pair high-speed countercurrent chromatography [DOI]
  28. 28 Rapid estimation of lycopene concentration in watermelon and tomato puree by fiber optic visible reflectance spectroscopy [DOI]
  29. 29 Tomato lycopene is a natural antioxidant and can alleviate hypercholesterolemia. [DOI]
  30. 30 Lycopene content of selected foods available on the Polish market and estimation of its intake.
  31. 31 Carotenoids : properties, effects and diseases
  32. 32 Development and validation of liquid chromatographic method for the determination of lycopene in plasma [DOI]
  33. 33 Lycopene: A Natural Red Pigment [DOI]
  34. 34 Extraction of basil leaves (ocimum canum) oleoresin with ethyl acetate solvent by using soxhletation method [DOI]
  35. 35 LYCOPENE FROM BLAKESLEA TRISPORA CHEMICAL AND TECHNICAL ASSESSMENT (CTA)
  36. 36 SYNTHETIC LYCOPENE: THE FUTURE BUT UNAWARE FACT
  37. 37 Review article: WATERMELON LYCOPENE AND ALLIED HEALTH CLAIMS
  38. 38 Journal of Food Science and Technology [DOI]

Cited by 13

Método analítico para a quantificação de betacaroteno e licopeno empregando imagens digitais e aplicativo de smartphone

João Vítor Szwarc, Taís Selhorst, Sandra Stets · STUDIES IN ENGINEERING AND EXACT SCIENCES · 2025

Isolation and Characterization of Carotenoids

Pragya Pandey, Nidhi Dangi, Prixit Guleria · Methods and Protocols in Food Science · 2025

Lycopene: A Powerful Nutraceutical with Diversified Health Benefits

Jyoti Singh, Sahibpreet Singh, Disha Arora · Current Traditional Medicine · 2025

Showing 5 of 13 known citations — external sources report more than can currently be individually listed.

Article metrics

Real usage data collected on this platform.

45

Page views

0

PDF downloads

4

Outbound clicks

13

Citations

Views over time

Views by country

Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".

Traffic sources

Referring site, by host.

Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.