Skip to content
Research Article Open access CC BY 4.0

Synthesis, Characterization and Antimicrobial Activity of Metal Complexes of N-(4-methoxybenzylidene) Isonicotinohydrazone Schiff Base

Md. Sajjad Hossain, Farzana Khanm Camellia, Nayon Uddin, Md. Kudrat-E-Zahan, Laila Arjuman Banu, Md. Masuqul Haque

Asian Journal of Chemical Sciences · pp. 1–8 · Published 3 Apr 2019

10.9734/ajocs/2019/v6i118987

Abstract

Two complexes of Cu(II) and Ni(II) with the ligand N- (4-methoxybenzylidene) isonicotinohydrazide, having the formula [M(La)2]2+ (M = Cu(II) and Ni(II)) were synthesized. The ligand was synthesized by the condensation of isonicotinic acid hydrazide (isoniazid) with 4- methoxybenzaldehyde (p- anisaldehyde). The complexes were characterized by FTIR, UV-Vis spectroscopy, molar conductivity, magnetic susceptibility and evaluated for their in vitro antibacterial activity against human pathogens like gram negative Escherichia coli (E. coli) and gram positive Bacillus cereus (B. cereus)strains. The results indicate that all complexes consist of N and O coordination with metals has better antimicrobial activity.

Schiff base ligands Cu(II) and Ni(II) isoniazid antimicrobial activity

Cited by 14

Biological Utility of Schiff’s Bases with Special Reference to Mixed Ligand Complexes: A Review

Dr. Vikas D. Ragole · International Journal of Advanced Research in Science, Communication and Technology · 2024

Structural and Biological Studies on Transition Metal Complexes of 4-Aminoantipyrine Derivative

V. Soundaranayaki, A. Kulandaisamy · Asian Journal of Chemistry · 2020

Article metrics

Real usage data collected on this platform.

0

Page views

0

PDF downloads

0

Outbound clicks

14

Citations

Views by country

Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".

No views recorded yet.

Traffic sources

Referring site, by host.

No traffic recorded yet.

Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.