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Research Article Open access CC BY 4.0

Synthesis and Biological Activity of Novel 5-(Alkylthio)-1,3,4-thiadiazol-2(3H)-thione Derivatives

Elen N. Hambardzumyan, Asya S. Vorskanyan, Ani A. Grigoryan, Aleksandr P. Yengoyan

Chemical Science International Journal · pp. 1–9 · Published 3 Jun 2016

10.9734/ACSJ/2016/26657

Abstract

Some nonfused biheterocyclic system derivatives containing a combination of 1,3,4-thiadiazole and pharmacophores such as 1,3,4-oxadiazole and/or pyrazoles in the same molecule were obtained based on 2-((5-(alkylthio)-1,3,4-thiadiazol-2-yl)thio)acetohydrazide. The synthesized compounds show pronounced plant growth stimulant properties.

5-(alkylthio)-1,3,4-thiadiazole-2(3H)-thiones derivatives heterocyclization nonfused biheterocyclic systems 1,3,4-oxadiazole pyrazole plant growth stimulant properties

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