Investigating the Impact of Senna alata Extract on Hematology and Histopathology of Juvenile of Clarias gariepinus

Abstract

This paper sheds light on the mechanism of action, potential effects and implication of Senna alata on fish health and ecosystem. Senna alata is renowned for its medicinal properties and ornamental value but is also recognized for its potential toxicity, particularly to aquatic organisms Understanding the toxicity of Senna alata to Clarias gariepinus fingerlings is essential for sustainable aquaculture practices and environmental conservation efforts. 250 juveniles of C. gariepinus were procured from E. I farm Limited in Ikot Ekpene, Akwa Ibom State. Water quality tests were carried out to ensure that optimum water conditions were maintained and that the results obtained were solely due to the effects of the treatments (toxicants) on the fish samples. Chronic toxicity bioassay was done to determine the toxicity of the extract on the blood parameters and tissues of sensitive organs of the exposed fish. The bioassay was designed to be intermediate termed chronic test with 14 days exposure using sub-lethal concentrations of the treatment (0.0gm/, 0.18mg/L, 0.27mg/L. 0.4mg/L, 0.60mg/L, 0.90mg/L). Toxicology dose response (fish mortality) was subjected to detailed analysis using Statistical Package for Social Sciences (SPSS) 22.0. Data were analyzed using descriptive statistics. Senna alata exerted a toxic effect on the fish in the present study and toxicity increased with increased concentration. These findings underscore the potential adverse effects of prolonged exposure to Senna alata on the physiological and cellular integrity of the fish. Intriguingly, the absence of pathological changes in the control groups suggests a distinct response attributable to the treatment. This highlights the importance of continued monitoring and assessment of the impacts of Senna alata on aquatic organisms and ecosystem, emphasizing the need for further research to elucidate the underlying mechanisms and potential long-term consequences.