Intestinal Obstruction as a Manifestation of Metastatic Gastrointestinal Neuroendocrine Tumor – A Case Report and Literature Review

Abstract

Neuroendocrine tumors (NETs) are rare tumors that are capable of secreting hormones into the bloodstream. They can affect any organ but are most commonly found in the digestive system, particularly in the small intestine. Neuroendocrine tumors (NETs) are often identified in later stages due to the emergence of nonspecific symptoms.  Chromogranin A serves as the primary biochemical indicator for NETs. Evaluating the extent of the disease typically involves conventional imaging techniques such as CT scans and MRIs, as well as isotopic imaging methods. Curative surgery remains the gold standard in the management of small intestine neuroendocrine tumors (SI-NETs). It should be considered as soon as possible, even in cases of metastatic stage. Somatostatin analogs (SSAs) are pivotal in both managing symptoms and therapeutically addressing metastatic Neuroendocrine Tumors (NETs). we present a case of a neuroendocrine tumor with intestinal obstruction along with a literature review.