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Research Article Open access CC BY 4.0

Intense Physical Exercise Reduces Complications, Hospitalizations and Potential Mortality from Covid-19

Romeu Paulo Martins Silva, Fabio Nascimento Da Silva, Carlos Soares Pernambuco, Marcelo Hubner Moreira, Estélio Henrique Martin Dantas, Anita Höekelmann, Gianluca Bianco, Cesar Rodrigo Vargas Vitoria, Pablo Jorge Marcos Pardo, Silvânia Matheus de Oliveira Leal, Tomires Campos Lopes, Artur Bessa, Estevão Scudese, Hossein Mohammadi, Bem Hur Soares, Fabiana Rodrigues Scartoni, Andrea Carmen Guimarães, Brisa D’Louar Costa Maia, Odelio Joaquim Costa, Jani Cleria Pereira Bezerra, Cesar Augusto de Souza Santos, Domingos Edno Castro Ribeiro, Eliane Gomes Silva Borges, Daniel Tobelém Maués Ferreira, Maria de Nazaré Dias Bello, Allan Carlos da Silva Tiago, Vernon Furtado-da-Silva, Divaldo Martins de Souza, Mauro Cesar Gurgel de Alencar Carvalho, João Rafael Valentim-Silva

Journal of Advances in Medicine and Medical Research · pp. 253–265 · Published 13 Feb 2025

10.9734/jammr/2025/v37i25738

Abstract

Aims: The present study investigate the relationship between pre-COVID-19 exercise levels and intensity and disease outcome. Methodologically we used an online survey comprising 20 questions was sent to participants to determine their exercise history, including type, intensity, and exacerbation of COVID-19 symptoms. Study Design: A populational survey-based study. Place and Duration of Study: A multicentric with many institutes and universities from Germany, Chile, Iran, Italy, Spain, Unted Staes of America, Canadá and Brazil. The duration from 2020 until 2024. Methodology: A large survey to determinate the physical fitness level, type, duration, and intensity of the physical exercise was applied under invitation of many associated researchers around the world. A electronic version were used to improve the acquisition in partners health centers and universities. We analyzed the possible interactions using a chi-square test to infer the results. Results: We note that individuals physically active had significantly better disease outcomes than physically inactive individuals. Low or moderate-intensity exercise did not show significant differences in exacerbations, but high-volume or high-intensity exercise was associated with decreased complications requiring hospitalization. Conclusion: Our study concludes that physical activity reduces the risk of intensive care and hospitalization due to SARS-CoV-2 infection, and exercise intensity plays a crucial role in mitigating the severity of the disease. The study suggests that a more physically active world population could prevent many deaths associated with COVID-19, and save life.

Sars-Cov-2 infection upper respiratory infection tract exercise-induced immunosuppression exercise-induced lesser hospitalization exercise-induced lesser co-morbidities

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