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Research Article Open access CC BY 4.0

In-vitro Pharmacological Investigation of Ludwigia adscendens

Md. Anik Bhuiyan, Hasib Khan Shomudro, Sadia Afreen Chowdhury

Asian Plant Research Journal · pp. 44–55 · Published 9 Nov 2023

10.9734/aprj/2023/v11i6229

Abstract

Aims: This research objective was to investigate some in-vitro properties of methanol-extracted plant extracts of Ludwigia adscendens (the water primrose). The primary method of assessment for the methanolic extract of Ludwigia adscendens (MELA) was investigated for phytochemical screening. It was determined to look into the plant's potential for in vitro activities, such as antioxidant, antimicrobial, anti-inflammatory anti-arthritis, cytotoxic, thrombolytic and membrane stabilizing activity due to the pharmaceutical interest in its component parts. Methodology: Phytochemical screening was performed utilizing a battery of test reagents. Antioxidant, antimicrobial, anti-inflammatory, anti-arthritic, cytotoxic, thrombolytic and membrane stabilizing activities were measured at various doses using the DPPH Free Radical Scavenging Assay, the Disk Diffusion Method, Egg Albumin Protein Denaturation Assay, the Inhibition of Protein Denaturation Assay, the Brine Shrimp Lethality Bioassay, Clot lysis assay and heat induced and hypotonic induced haemolysis method. Results: The findings of research on MELA's phytochemical screening showed the presence of a wide range of various phytochemical components. The higher antioxidant activity of MELA is shown by its IC50 value of 85.76 µg/mL. Significant antibacterial action was shown by MELA. As compared to the standard ascorbic acid, this extract showed significantly greater anti-arthritic and anti-inflammatory effects. MELA exhibited much higher LC50 value which is 1.147 µg/mL than the typical vincristine-sulphate in a lethality test with brine shrimp. Comparatively speaking, this herb has quite powerful thrombolytic action. Significant membrane stabilizing action has also been shown by MELA. Conclusion: To wrap it up, it is clear that this plants phytochemical can be used for wide range of drug discovery field due to its potent pharmacological actions.

Antioxidant antimicrobial anti-inflammatory antiarthritic cytotoxic thrombolysis

References (20)

  1. 1 Genesis and development of DPPH method of antioxidant assay [DOI]
  2. 2 Antibacterial plant compounds, extracts and essential oils: An updated review on their effects and putative mechanisms of action [DOI]
  3. 3 Phytochemical screening, total phenolics and antioxidant activities of bark and leaf extracts of Goniothalamus velutinus (Airy Shaw) from Brunei Darussalam [DOI]
  4. 4 Antimicrobial Activity and Brine Shrimp Lethality Bioassay of the Leaves Extract of Dillenia indica Linn. [DOI]
  5. 5 Anti-arthritic activity of aqueous-methanolic extract and various fractions of Berberis orthobotrys Bien ex Aitch [DOI]
  6. 6 Evaluation of Anti-inflammatory Effect of Ashwagandha: A Preliminary Study in vitro [DOI]
  7. 7 Stabilization of serum albumin by anti-inflammatory drugs [DOI]
  8. 8 Phytochemical screening, antioxidants and antimicrobial potential of Lantana camara in different solvents [DOI]
  9. 9 Phytochemical Screening, Antimicrobial and in vitro Anti-inflammatory Activity of Endophytic Extracts from Loranthus sp. [DOI]
  10. 10 Phytochemicals screening and antimicrobial activities of selected medicinal plants of Khyberpakhtunkhwa Pakistan [DOI]
  11. 11 IN VITRO ANTI INFLAMMATORY ACTIVITY OF METHANOLIC EXTRACT OF CENTELLA ASIATICA BY HRBC MEMBRANE STABILISATION
  12. 12 In vitro antioxidant, antimicrobial, membrane stabilization and thrombolytic activities of Dioscorea hispida Dennst. [DOI]
  13. 13 Centaurea hypoleuca DC: Phenolic content, antimicrobial, antioxidant and enzyme inhibitory activities [DOI]
  14. 14 Evaluation of anti rheumatic activity of Piper betle L. (Betelvine) extract using in silico, in vitro and in vivo approaches [DOI]
  15. 15 Phytochemical investigation of Ludwigia adscendens subsp. diffusa aerial parts in context of its biological activity [DOI]
  16. 16 Evaluation of membrane stabilizing, anthelmintic, antioxidant activity with phytochemical screening of methanolic extract of Neolamarckia cadamba fruits [DOI]
  17. 17 Free-Radical Processes in Multistage Carcinogenesis [DOI]
  18. 18 Chemical constituents from Ludwigia adscendens [DOI]
  19. 19 Cytotoxic activity of marine macro‐algae on Artemia salina (Brine shrimp) [DOI]
  20. 20 Effects of Five Bangladeshi Plant Extracts on In vitro Thrombolysis and Cytotoxicity [DOI]

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