Impact of Nutritional Interventions on Epigenetic Influences in the Gestational and Puerperium Period: A Systematic Review

Abstract

Background: Epigenetic analyzes associated with maternal and child nutrition are the subject      of several studies due to their crucial role in fetal development. Significant changes in diet during the gestational period or even in the puerperium can lead to metabolic diseases or even neuropsychiatric disorders. Aims: The present study sought to carry out a systematic review of such interactions in the pre- and post-pregnancy periods. Study Design: Systematic review. Methodology: Bibliographic research was used as a method and data were obtained from the VHL information portal from 2017 to 2021. Original articles published in the last 6 years, related to nutritional impacts on epigenetic mechanisms, whether in women during the gestational and postpartum period or newborns, were included in this study. In the gestational period and puerperium or newborns. Results: Nine studies that met the selection criteria and were associated with the topic were selected. Conclusion: Based on this study, it was possible to understand the relationship between diet and the expression of epigenetic changes in order to promote studies in this area that facilitate the understanding of various diseases of genomic origin.