Skip to content
Research Article Open access CC BY 4.0

Histopathological Characteristics of Breast Lesions in a Tertiary Health Institution in Southwest Nigeria: A 9-year Review

Olabisi Ayo-Aderibigbe, Taiwo Oloyede, Adebayo Adekunle, Oluwole Odujoko, Taiwo Babatunde, Samson Ojedokun, Afolabi Salawu

Journal of Cancer and Tumor International · pp. 73–80 · Published 20 Dec 2022

10.9734/jcti/2022/v12i4222

Abstract

Background: The breast is affected by several diseases, including developmental, inflammatory, and neoplastic. While benign breast neoplasms are usually more common, breast cancer is the most common nonskin cancer and the leading cause of cancer-related deaths in women after lung cancer in the world. Objective: The review aimed to assess the histopathological diagnosis of breast lesions over a period of 9years Methods: This was a retrospective review of eight hundred and fourteen histopathologic cases of breast lesions accessed through laboratory records of all breast lesions cases seen. The demographic data were obtained and the patient’s histology slides were reviewed. The tumors were classified according to the WHO International Classification of breast tumors and Malignant breast tumors were graded according to the Nottingham grading system. Data were analyzed using SPSS version 25. Results: The majority of breast cancer cases were seen in patients below 40 years, malignant cases were predominant in older age groups (40 – 59 years; 57.4%, 60 years and above; 23.3%) and malignancy was significantly associated with age group, p-value < 0.05. The prevailing neoplasm was Benign type (68.3%) while malignant neoplasm accounted for 30.2% and invasive ductal carcinoma (89.1%) was most prevalent. Moreso, the majority were in grade 2; 152 (76.8%) using the Nottigham grading system. However, the commonest benign neoplasm was fibroadenoma (53.7%) followed by fibrocystic change (20.1%). Conclusion:  Breast lesions are common in this environment.  Benign breast neoplasms are more commoner than malignant diseases.  One in three of every sub-Saharan woman diagnosed with malignant breast lesion may not survive five years post-diagnosis. The prognosis of breast malignancies in sub-Saharan is poor due to late Presentation, ignorance, and poverty.

breast lesion histopathology Ogbomoso Nigeria

References (21)

  1. 1 Robbins & Cotran Pathologic Basis of Disease
  2. 2 Cancer incidence in Nigeria: A report from population-based cancer registries [DOI]
  3. 3 Environmental factors inducing human cancers.
  4. 4 The severity, outcome and challenges of breast cancer in Nigeria [DOI]
  5. 5 Myoepithelial and epithelial–myoepithelial, mesenchymal and fibroepithelial breast lesions: updates from the WHO Classification of Tumours of the Breast 2012 [DOI]
  6. 6 Histologic grade, stage, and survival in breast carcinoma [DOI]
  7. 7 Management and Outcomes of Male Breast Cancer in Zaria, Nigeria [DOI]
  8. 8 Breast masses in Zaria, Nigeria
  9. 9 Molecular subtyping of carcinoma of the female breast in a tertiary teaching hospital in Northern Nigeria [DOI]
  10. 10 Cancer in Kano, Northwestern Nigeria: A 10-year update of the kano cancer registry [DOI]
  11. 11 Histopathological Review of Breast Tumors in Kano, Northern Nigeria [DOI]
  12. 12 Analysis of Female Breast Biopsies in Usmanu Danfodiyo University Teaching Hospital (UDUTH) Sokoto, Nigeria; A Ten Year Retrospective Study. [DOI]
  13. 13 Pattern of breast masses ing Lagos: A private health facility review of 189 consecutive patients. [DOI]
  14. 14 Clinicopathologic study of breast lumps in Abakaliki, South Eastern Nigeria [DOI]
  15. 15 Histopathological characteristics of female breast carcinomas seen at the University of Port Harcourt Teaching Hospital, Port Harcourt, Nigeria [DOI]
  16. 16 Triple negative breast cancer at the Jos University Teaching Hospital [DOI]
  17. 17 Clinicopathologic Features of Female Breast Cancer in Kumasi, Ghana [DOI]
  18. 18 Breast lesions in a district hospital: Demographic and histopathologic characteristics [DOI]
  19. 19 The Spectrum of Breast Diseases in Nigeria North Central: A Histopathological Survey [DOI]
  20. 20 Histopathological review of male breast cancer in Sokoto, Nigeria [DOI]
  21. 21 Prevalence of Benign Breast Lesions, Epithelial Proliferations with or without Atypia in Calabar-A Retrospective Review [DOI]

Cited by 0

No indexed citations yet.

Related research

Article metrics

Real usage data collected on this platform.

55

Page views

0

PDF downloads

9

Outbound clicks

0

Citations

Views over time

Views by country

Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".

Traffic sources

Referring site, by host.

Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.