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Research Article Open access CC BY 4.0

Heart Failure: Causes, Symptoms, and Management Strategies

Raheel Chaudhry, Arhum Mahmood, Imdad Ullah, Evelyn Pineiro Urra, Mohd Diya Masmoum, Anfal Atif, Lazaro H. Cabrera, Hassan Ahmed

Journal of Advances in Medicine and Medical Research · pp. 335–345 · Published 21 Aug 2024

10.9734/jammr/2024/v36i85551

Abstract

Cardiac failure (HF) is a multifaceted clinical center described by the incapacity of a heart to sufficiently pump blood leading to inefficient perfusion of tissues. It has two main categories that are represented by ejection fraction: Heart Failure with Reduced Ejection Fraction (HFrEF), or Heart Failure with Preserved Ejection Fraction (HFpEF). The following review is a summary of research on the diverse causes, symptoms as well as management approaches involved in heart failure. Heart disorder comes about as a result of the following factors: coronary artery disease, hypertension, cardiomyopathy, valvular heart diseases, arrhythmias, and congenital heart defects the main symptoms include shortness of breath, weariness/tiredness, and swelling of the feet among others. Management strategies cover lifestyle modifications, medicines using treatment (e.g. diuretics, ACE inhibitors, beta-blockers), and further treatments like cardiac resynchronization therapy (CRT) consisting of implantable cardioverter defibrillators (ICDs) along with mechanical circulatory support (MCS); however, there is also heart transplant aside them.’ Future progression in genetic treatment gene therapy, as well as stem cell study, sounds promising over improving results obtained from HF treatment.

Heart failure symptoms of heart failure HFpEF

Cited by 2

In vitro approaches to mimic cardiac mechanical load dynamics for enhancing maturation and disease modelling

Mariel Cano-Jorge, Sofia Gómez, Jaap den Toonder · Cardiovascular Research · 2025

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