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Research Article Open access CC BY 4.0

A Case of Linear IgA Dermatosis in a Young Child

V. Thadchanamoorthy, V. Vijayakanth, N. Thamilvannan

Asian Journal of Research in Dermatological Science · pp. 44–47 · Published 27 Jun 2020

Abstract

Diagnosis of Linear immunoglobulin A (IgA) bullous disease (LABD) is difficult as they present to relevant clinician late. This is the case of a 4-year-old Sri Lankan boy with a 2 months history of non-itching, blistering lesions on his extremities. Medical history was unremarkable. Medical treatments included a visit to a general practitioner, where he was treated with antibiotics unsuccessfully. We performed a skin biopsy and Direct immunofluorescent studies revealed a linear deposition of IgA antibody at the basement membrane. The clinical diagnosis of linear IgA dermatosis was established, with no eliciting cause. Resolution of blisters was achieved with oral prednisolone, dapsone and antibiotic treatment. This is the first case to our knowledge occurring in this age group with involvement of only extremities, sparing genital area.

Linear immunoglobulin a bullous disease linear IgA dermatosis dapsone immunofluorescence

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