Insulin Mediated Lipohypertrophy
Manda Anusha, Jannapala Anusha, Adiba Nousheen, Enara Bawani, Sangareddy Jayanth Kumar
Asian Journal of Research and Reports in Endocrinology · pp. 87–91 · Published 1 Jul 2023
Abstract
Insulin is used to treat diabetes Type I and II. This article explains how a lipohypertrophy is caused by the insulin and explains the precautions that should be taken during the administration of insulin. Lipohypertrophy (LH) is a typical side effect of insulin therapy in subcutaneous tissue. Several injections at the same place result in this problem. A potential underlying mechanism of lipohypertrophy is the production of insulin antibodies. Recognizing and effectively managing these problems are crucial. In order to detect mild forms of lipohypertrophy, every patient should have their lips thoroughly evaluated for the condition during a diabetes clinic evaluation. The best current preventative and therapeutic approaches for lipohypertrophy are non-reuse of needles and rotation of injection sites with each injection. Education for both doctors and patients on recognising and treating lipohypertrophy is advisable.
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