In vitro Antioxidant Activity of Salacia lehmbachii Ethanol Root Bark Extract
Godwin Christian Akuodor, Grace Akanimo Essiet, Augustine Dick Essien, Francis Vincent Udoh, Donald Emeka Ogiji, Solomon Kingsley Nwadum, Emmanuel Micheal Nworie
European Journal of Medicinal Plants · pp. 1–6 · Published 26 Apr 2017
10.9734/EJMP/2017/32014Abstract
Aim: This work was undertaken to investigate the in vitro antioxidant activity of S. lehmbachii ethanol root bark extract. Place and Duration of Study: Department of Pharmacology, University of Calabar, Nigeria, between June, 2013 and October, 2015. Methods: Antioxidant activity of the root extract was evaluated using DPPH (2, 2-diphenyl-1-picrylhdrayl) radical, Nitric oxide and hydrogen peroxide scavenging assays. Results: A significant inhibition at different concentration of the extract was observed with DPPH radical, nitric oxides and hydrogen peroxide scavenging activities when compared with ascorbic acid. Conclusion: The results of the study show that the ethanol root bark extract of S. lehmbachii may serve as a good scavenger of free radicals, hence reduces the effects of oxidative stress in the body and could be explored as a therapeutic agent in free radical induced diseases.
Cited by 1
Godwin Christian Akuodor, Grace Akanimo Essiet, John Azubuike Ekenjoku · Journal of Herbmed Pharmacology · 2021
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