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Research Article Open access CC BY 4.0

Rare Association of an Aggressive Giant Cell Tumor with Xeroderma Pigmentosum

A. Alshaikh, E. Bachkira, I. Jadib, O. Hadad, C. Elkassimi, A. Rafaoui, M. Rafai

Asian Journal of Case Reports in Surgery · pp. 516–520 · Published 31 Dec 2022

Abstract

Xeroderma pigmentosum (XP) is a genodermatosis that manifests as photo-induced skin and ocular alterations and skin cancers. An association with a giant cell tumor is a very rare entity. We report the case of a 17-year-old patient, followed since childhood for XP, who presented with a very aggressive giant cell tumor in the wrist for which he underwent amputation. A review of the literature of these rare lesions is presented and analyzed to see if this is an association or is a chance coincidence.

Xeroderma pigmentosum giant cell tumour aggressive distal radius

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