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Research Article Open access CC BY 4.0

Functional and Hemodynamic Efficacy of Non-Poliferative Diabetic Retinopathy Treatment by Endonasal Electrophoresis of Tanakan

Guzal Kangilbaeva, Fazilat Bakhritdinova, Behruz Oralov, Aziza Jurabekova

Ophthalmology Research: An International Journal · pp. 1–9 · Published 2 Jan 2023

10.9734/or/2023/v18i1374

Abstract

Aims: To study the effectiveness of the treatment of patients with non-proliferative diabetic retinopathy by tanakan endonasal electrophoresis according to functional and hemodynamic data. Study Design: Cross-sectional comparative analysis. Place and Duration of Study: Department of Ophthalmology, clinic of Tashkent Medical Academy, between 2017 and 2020. Methodology: We included 66 patients (123 eyes), 23 men and 43 women; age range 18-75 years with non-proliferative diabetic retinopathy. The patients were divided into 2 groups: to receive daily tablets of Tanakan (control), or daily endonasal electrophoresis of Tanakan (main) within ten days. Before and after the course of therapy, the patients underwent determination of visual acuity, Doppler ultrasound imaging of the eye and computer static perimetry. Results: Improvements in visual acuity were observed in 87,3%  of the main group patients, and in 22% of the control group. Statistically significant increase in blood flow velocity and a decrease in the resistance index were observed in the main group (P < 0.05). Retinal photosensitivity increased by 22% in the main group, and by 10% in the control group. The mean deviation from the age norm decreased by 33% in the main group and by 12% in the control group. Among the patients of the main group, 30% experienced a decrease in absolute scotomas and 100% in relative scotomas. Among the patients of the control group, 21% and 83% experienced a decrease in absolute and relative scotomas, respectively. Conclusion: Treatment with tanakan endonasal electrophoresis significantly improved visual acuity, eye hemodynamics, and retinal photosensitivity. This treatment is more effective than the traditional use of ginkgo- biloba tablets.

Nonproliferativ diabetic retinopathy endonazal electrophoresis antioxidant color doppler imaging microcirculation systolic velocity microaneurysms hemorrhages intraretinal microvascular abnormalities photosensitivity scotomas

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Cited by 2

АВТОМАТИЗИРОВАННАЯ ДИАГНОСТИКА ДИАБЕТИЧЕСКОЙ РЕТИНОПАТИИ (обзор)

Бахритдинова Фазилат Арифовна, Guzal Kangilbaeva, Urmanova Firuza Makhkamovna · Advanced Ophthalmology · 2024

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