Formulation Evaluation and In- Vitro Antioxidant activity of Microparticles of Syzygium Cumini  Plant Extract

Sweta Srivastava Koka; Pravin Kumar Sharma; Vaishali Sharma; Jaya verma; G. N. Darwhekar

doi:10.9734/jpri/2021/v33i27B31504

Research Article Open access CC BY 4.0

Formulation Evaluation and In- Vitro Antioxidant activity of Microparticles of Syzygium Cumini Plant Extract

Sweta Srivastava Koka, Pravin Kumar Sharma, Vaishali Sharma, Jaya verma, G. N. Darwhekar

Journal of Pharmaceutical Research International · pp. 77–85 · Published 1 May 2021

10.9734/jpri/2021/v33i27B31504

Abstract

Sygygium cumini, commonly known as Malabar plum, Java plum, black plum, jamun or jambolan, is an evergreen tropical tree in the flowering plant family Myrtaceae. The present study the antioxidant effects of microparticles of S. cumini plant extract were evaluated using in vitro, 2, 2-diphenylpicrylhydrazine photometric assay, total antioxidant activity and super oxide free radical scavenging activity. The microparticles showed different levels of radicals scavenging activity in a dose-dependent manner over the range of 50–150 µg/mL concentration, indicating the high antioxidative capacity of the extract. In all the experimental screening models microparticles of aqueous extract show the maximum inhibition of free radicals comparison of other experimental model at different concentrations. These findings suggest that the seed of Syginium cumini has potent antioxidant activity which may be responsible for some of its reported pharmacological activities and can be used as antioxidant supplement.

Syginium cumini microparticles antioxidant DPPH super oxide

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Sweta Srivastava Koka, Pravin Kumar Sharma, Vaishali Sharma, Jaya verma, G. N. Darwhekar (2021). Formulation Evaluation and In- Vitro Antioxidant activity of Microparticles of Syzygium Cumini Plant Extract. Journal of Pharmaceutical Research International , 77–85. https://doi.org/10.9734/jpri/2021/v33i27B31504

Affiliations

Sweta Srivastava Koka — Acropolis Institute of Pharmaceutical Education and Research Indore MP, India.
Pravin Kumar Sharma — Acropolis Institute of Pharmaceutical Education and Research Indore MP, India.
Vaishali Sharma — Acropolis Institute of Pharmaceutical Education and Research Indore MP, India.
Jaya verma — Acropolis Institute of Pharmaceutical Education and Research Indore MP, India.
G. N. Darwhekar — Acropolis Institute of Pharmaceutical Education and Research Indore MP, India.

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