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Research Article Open access CC BY 4.0

Expression of BCL-2 and KI-67 in Cyclical Endometrium and in Endometrial Hyperplasia

P. Shalini, Natrajan Suresh, S. Mary Lilly

Journal of Pharmaceutical Research International · pp. 1–11 · Published 6 Apr 2021

10.9734/jpri/2021/v33i21A31363

Abstract

The Present study attempts to determine the relationship between proliferation and the inhibition of apoptosis in normal endometrium and hyperplasia, using monoclonal antibodies against the proliferation marker, Ki-67 and the anti-apoptotic protein, Bcl-2 and to determine the expression of B-cell lymphoma 2 (Bcl – 2) and Ki – 67 in cyclical endometrium in proliferative and secretory phase. The Present study includes the expression of Bcl – 2 and Ki – 67 in endometrial hyperplasia.

Endometrium apoptosis Bcl – 2 Ki-67 hematoxylin biopsy and xylene

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