Skip to content
Research Article Open access CC BY 4.0

Exploration of Chemical Composition and Unveiling the Phytopharmaceutical Potentials of Essential Oil from Fossilized Resin of Pinus succinefera

Vikas Jha, Mohd Aslam Shaikh, Sakshi Devkar, Reetikesh Patel, Shraddha Walunj, Diksha Rai, Joshua Koli, Vrushali Dhamapurkar, Tisha Jain, Namrata Jadhav, Arpita Marick, Divya Dhopeshwarkar

International Research Journal of Pure and Applied Chemistry · pp. 19–34 · Published 7 Jul 2022

10.9734/irjpac/2022/v23i330464

Abstract

Background: Most of the plant natural flora contributes significantly to medicinal benefits. To address the shortcoming usage of synthetic drugs, natural products are in demand which offer a broad spectrum of activities with negligible side effects. Pinus succinefera is a fossilized resin from coniferous woods that belongs to the genus Pinus of the Pinaceae family and is widely known as Amber. The present study explores the physiochemical properties and broad spectrum of biological activities of the essential oil. Method: The essential oil obtained using the hydro-distillation process, and chemical composition was examined by Gas Chromatography-Mass Spectrometric analysis as well as the functional groups present in the essential oil were determined using Fourier Transform Infrared Spectrometry. Thermal characterisation was performed using the Thermo Gravimetric Analysis and Differential Scanning Calorimetry. The antimicrobial potential of the essential oil was evaluated against different microorganisms meanwhile antimalarial activity against Plasmodium falciparum was examined. The free radical scavenging capability of the essential oil was assessed using 2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH) reagent. High-performance thin-layer chromatography was used to examine the qualitative components of the essential oil. Results: The Gas Chromatography-Mass Spectrometric analysis profile indicated 5 major compounds in the essential oil, which consisted of 99% of the total oil. The thermal analysis of the essential oil established thermal stability. The essential oil showed moderate antioxidant and a moderate to significant potential was observed against microbial species including Plasmodium falciparum. In High-performance thin-layer chromatography five bands of essential oil components with Retention factor ranging from 0.2 to 0.7 at 254nm were represented. Conclusion: The results indicated that the essential oil obtained from Pinus succinefera has the potential to be used in the pharmaceutical industry to manufacture medicinal substances, as well as it can show a significant capability in other domains.

Antimicrobial antioxidant HPTLC FTIR antimalarial DSC essential oil GC-MS Pinus succinefera

References (45)

  1. 1 Plant Polyphenols as Dietary Antioxidants in Human Health and Disease [DOI]
  2. 2 Plant Phenolics: Extraction, Analysis and Their Antioxidant and Anticancer Properties [DOI]
  3. 3 The growing use of herbal medicines: issues relating to adverse reactions and challenges in monitoring safety [DOI]
  4. 4 A Historical Overview of Natural Products in Drug Discovery [DOI]
  5. 5 Antimicrobial Activity of Some Essential Oils—Present Status and Future Perspectives [DOI]
  6. 6 Essential Oils’ Chemical Characterization and Investigation of Some Biological Activities: A Critical Review [DOI]
  7. 7 Stability of Essential Oils: A Review [DOI]
  8. 8 The Role of Polyphenols in Human Health and Food Systems: A Mini-Review [DOI]
  9. 9 Essential oils used in aromatherapy: A systemic review [DOI]
  10. 10 Antioxidant and Anti-Inflammatory Activities of Essential Oils: A Short Review [DOI]
  11. 11 Polyphenols and Human Health: Prevention of Disease and Mechanisms of Action [DOI]
  12. 12 Essential Oils as Natural Sources of Fragrance Compounds for Cosmetics and Cosmeceuticals [DOI]
  13. 13 Role of essential oils in food safety: Antimicrobial and antioxidant applications [DOI]
  14. 14 A new method for determining the minimum inhibitory concentration of essential oils [DOI]
  15. 15 Therapeutic and Medicinal Uses of Terpenes [DOI]
  16. 16 Monoterpenes and Their Derivatives—Recent Development in Biological and Medical Applications [DOI]
  17. 17 Antioxidant Activity and Protecting Health Effects of Common Medicinal Plants [DOI]
  18. 18 Chemistry of Essential Oils and Factors Influencing Their Constituents [DOI]
  19. 19 High-Performance Thin-Layer Chromatography (HPTLC) [DOI]
  20. 20 High-performance thin layer chromatography: A powerful analytical technique in pharmaceutical drug discovery [DOI]
  21. 21 Extraction of Essential Oils of Rosmarinus officinalis L. by Two Different Methods: Hydrodistillation and Microwave Assisted Hydrodistillation [DOI]
  22. 22 A new proposal concerning the botanical origin of Baltic amber [DOI]
  23. 23 Novel Cinnamic Acid Derivatives as Antioxidant and Anticancer Agents: Design, Synthesis and Modeling Studies [DOI]
  24. 24 Antioxidants of Fruit Extracts as Antimicrobial Agents against Pathogenic Bacteria [DOI]
  25. 25 Crude oil characterization using TGA-DTA, TGA-FTIR and TGA-MS techniques [DOI]
  26. 26 The Effects of Essential Oils and Terpenes in Relation to Their Routes of Intake and Application [DOI]
  27. 27 Pinus Species as Prospective Reserves of Bioactive Compounds with Potential Use in Functional Food—Current State of Knowledge [DOI]
  28. 28 Characterization and determination of the quality of rosins and turpentines extracted from Pinus oocarpa and Pinus patula resin [DOI]
  29. 29 Correlation Between Chemical Composition and Antifungal Activity of the Essential Oils of EightCinnamomum. Species [DOI]
  30. 30 Antifungal activity of cinnamic acid derivatives involves inhibition of benzoate 4-hydroxylase (CYP53) [DOI]
  31. 31 Antioxidant Activity of Essential Oil and Extracts of Valeriana jatamansi Roots [DOI]
  32. 32 Synthesis and characterization of abietadiene, levopimaradiene, palustradiene, and neoabietadiene: hydrocarbon precursors of the abietane diterpene resin acids [DOI]
  33. 33 Biosynthesis of benzyl cinnamate using an efficient immobilized lipase entrapped in nano-molecular cages [DOI]
  34. 34 In Vitro Antibacterial Activity, Gas Chromatography–Mass Spectrometry Analysis of Woodfordia fruticosa Kurz. Leaf Extract and Host Toxicity Testing With In Vitro Cultured Lymphocytes From Human Umbilical Cord Blood [DOI]
  35. 35 HPTLC Fingerprints of Various Secondary Metabolites in the Traditional Medicinal HerbHypochaeris radicataL. [DOI]
  36. 36 Presence of phthalate derivatives in the essential oils of a medicinal plant Achillea tenuifolia [DOI]
  37. 37 Antibacterial Activity of Benzyl Benzoate and Crotepoxide from Kaempferia rotunda L. Rhizome [DOI]
  38. 38 Application of Thermal Methods to Analyze the Properties of Coffee Silverskin and Oil Extracted from the Studied Roasting By-Product [DOI]
  39. 39 Rapid Staining of Malarial Parasites by a Water Soluble Stain.
  40. 40 Pharmacological interactions of essential oil constituents on the in vitro growth of Plasmodium falciparum [DOI]
  41. 41 Chemical Composition of Indonesian Pinus merkusii Turpentine Oils, Gum Oleoresins and Rosins from Sumatra and Java [DOI]
  42. 42 Characterization of essential oil from Matricaria sevanensis by microwave-assisted distillation [DOI]
  43. 43 High-Performance Thin-Layer Chromatographic Quantification of Some Essential Oils fromAnethum graveolensExtracts [DOI]
  44. 44 Safety, biodegradability, and biocompatibility considerations of long-acting drug delivery systems [DOI]
  45. 45 Natural Products [DOI]

Cited by 10

Investigation of physico-chemical properties and evaluation of the biological potential of essential oil extracted from Artemisia pallens

Vikas Jha, Purvesh Kadam, Tisha Jain · Journal of Umm Al-Qura University for Applied Sciences · 2023

Antioxidant Activity of Essential Oils from Pinaceae Species

Robert Ancuceanu, Adriana Iuliana Anghel, Marilena Viorica Hovaneț · Antioxidants · 2024

Role of Essential Oils and Bioactive Components for Manufacturing Cosmetic Items

Aditi, Kriti Dabral · Journal for Research in Applied Sciences and Biotechnology · 2023

Pinus mugo Turra and its Therapeutic Potential: A Narrative Review

Maria Giulia Manzione, Sara Vitalini, Farukh Sharopov · Natural Product Communications · 2024

Showing 5 of 10 known citations — external sources report more than can currently be individually listed.

Article metrics

Real usage data collected on this platform.

16

Page views

0

PDF downloads

2

Outbound clicks

10

Citations

Views over time

Views by country

Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".

Traffic sources

Referring site, by host.

Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.