Evaluation on Safety and Efficacy of Selective Anti-Hypertensive Drugs in Patients with Cardiovascular Disease at a Tertiary Care Hospital, India-an Observational Study
R. E. Ugandar, Umadevi Iluru, Mariamma Bethe, C. Bhargava Reddy, Kiran C. Nilugal
Journal of Pharmaceutical Research International · pp. 383–391 · Published 20 Sep 2021
10.9734/jpri/2021/v33i44A32629Abstract
Background: Hypertension means persistent elevation of Blood Pressure in arteries. It is the second leading cause of death. The symptoms include Severe Headache, Drowsiness, Vision problem, Nose bleed, fatigue, Confusion. It may lead to various types of Cardiovascular disorders such as Myocardial Infarction, Coronary Artery Disease, Heart Failure. The treatment of Hypertension can be done by Anti-Hypertensive Drugs which include Angiotensin -II Receptor Blockers, Beta Blockers, Angiotensin Converting Enzyme Inhibitors etc. Results: We have done the study to find out the safe and effective drug among various categories of Anti-Hypertensive drugs to treat hypertension in various cardiovascular disease patients. We have collected sample size of 220 out of which 100 were Myocardial Infarction patients,100 were coronary artery disease patients and 20 were Heart Failure patients. The categories of anti-hypertensive drugs selected for our study were Angiotensin-II Receptor Blockers, Beta Blockers and Angiotensin Converting Enzyme Inhibitors. Angiotensin-II Receptor Blockers were prescribed to 31 Myocardial Infarction patients, 31 coronary artery disease patients,8 Heart Failure patients. Beta Blockers were prescribed to 58 Myocardial Infarction patients,58 coronary artery disease patients,7 Heart Failure patients. Angiotensin Converting. Enzyme Inhibitors were prescribed to 10 Myocardial Infarction patients,10 Coronary Artery Disease patients,5 Heart Failure patients. Conclusion: From all the observations, Beta Blockers were observed to be the drugs with maximum efficacy and maximum safety.
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