Evaluation of Ocular Findings in Vitiligo
Najat Belkheir, Adam Albarghathi, Ghait Alsdae, Faraj Alshwin, Gamal Duweb
Ophthalmology Research: An International Journal · pp. 1–7 · Published 19 Jul 2022
10.9734/or/2022/v17i130245Abstract
Vitiligo is a pigmentary disorder of the skin and mucous membranes with worldwide incidence of 0.5-2%. The aim of this cross sectional study was to assess the ocular involvement in vitiligo patients. Two hundred patients clinically diagnosed vitiligo attending vitiligo clinic, dermatology department, Jomhorya hospital, Benghazi-Libya over a period of 6 months enrolled in this cross-sectional study. All patients were exposed to detailed disease history and thorough dermatological examination. Out of the total cases, 100 patients had a standard Ophthalmologic examination in cooperation with an ophthalmologist in Benghazi eye hospital. Results of our study showed a slightly higher prevalence of vitiligo in females (male: female ratio 1:2.8). The mean age of onset for males was 22.4 years and for females 24.8 years and 58.5% of patients develop vitiligo below 20 years of age. Generalized vitiligo was the commonest clinical type of vitiligo (57.5%). The relationship between the duration of the disease and its type was statistically significant (P<0.05), there was also a significant relationship between the type of vitiligo and its severity (P< 0.01). Sixteen patients (8%) had segmental vitiligo and the face was the common site involved. The lower limbs were the most commonly affected sites of the body (57%). Ocular changes were seen in 40% of patients and specific ocular abnormalities like uveitis, iritis, and iris and retinal pigmentary abnormalities are present in 15% of patients, nonspecific ocular abnormalities were present in 33% of patients. There was no statistically significant correlation between specific ocular abnormalities, severity and duration of vitiligo.
References (20)
- 1 Fitzpatrick’s Dermatology in General Medicine [DOI]
- 2 High Frequency of Skin-homing Melanocyte-specific Cytotoxic T Lymphocytes in Autoimmune Vitiligo [DOI]
- 3 Evidence for an Autoimmune Pathogenesis of Vitiligo [DOI]
- 4 The Genetics of Generalized Vitiligo [DOI]
- 5 Segmental vitiligo: Clinical findings in 208 patients [DOI]
- 6 Vitiligo. It is important [DOI]
- 7 Hypomelanoses and hypermelanoses
- 8 The genetic concept of vitiligo [DOI]
- 9 Genome-Wide Analysis Identifies a Quantitative Trait Locus in the MHC Class II Region Associated with Generalized Vitiligo Age of Onset [DOI]
- 10 Living with vitiligo: results from a national survey indicate differences between skin phototypes [DOI]
- 11 Ocular disturbances in vitiligo [DOI]
- 12 Vitiligo: A sign of systemic disease [DOI]
- 13 Clinical predictors of outcome in vitiligo.
- 14 Clinical pattern of ocular manifestations in vitiligo.
- 15 Characterization of circulating CD8+T cells expressing skin homing and cytotoxic molecules in active non-segmental vitiligo [DOI]
- 16 Evaluation of ocular findings in patients with vitiligo [DOI]
- 17 Etiopathogenesis of vitiligo : Are we dealing with an environmental disorder ?
- 18 Prevalence of Impaired Hearing and Vision in Patients with Vitiligo.
- 19 Vitiligo and Other Hypomelanoses of Hair and Skin [DOI]
- 20 Ocular abnormalities in childhood vitiligo - when to screen? [DOI]
Cited by 1
Oran Mann, Sapir Glazer Levavi, Arnon D. Cohen · International Journal of Dermatology · 2026
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