Evaluation of Clinical Outcome of Cranioplasty Using Different Prosthetic Materials in Traumatic Brain Injury Patient: An Observational Study

Abstract

Background: Injuries of head, cerebral tumours, infections and ischemia are the most common causes of intracranial disorders and decompressive craniotomy may require to treat those patient followed by reconstruction later on. After loss of skull bone, cranial reconstruction or Cranioplasty is a choice of treatment worldwide for the restoration of the skull integrity. There are different types of materials which can be used for Cranioplasty but all have their own advantages and pitfalls. Objective: Evaluation of clinical outcome of Cranioplasty using different prosthetic materials i.e Polymethyl methacrylate (PMMA), Titanium (Ti), Polymethyl methacrylate Bone Cement(PMMA Bone cement) in traumatic brain injury patient. Methods: The patients will be divided into 4 groups according to the material used for Cranioplasty. (PMMA, Ti, Autologous bone graft, PMMA Bone cement). The intra operative clinical data and post-operative data will be collected from the previously collected records. (operative time, blood loss, including any complication or graft rejection). Statistical analysis will be done. Results: Collected data form 40 patients will be statistically analysed to obtain the result. Expected outcome is PMMA Bone cement, is an equally effective prosthetic material as compared to PMMA and Ti in terms of intra operative and post-operative clinical outcome for Cranioplasty in traumatic brain injury patients. Conclusion: This study would help in knowing the feasibility of using PMMA bone cement as a Cranioplasty material and will evaluate the clinical outcome of PMMA, Ti and PMMA bone cement in Cranioplasty.