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Research Article Open access CC BY 4.0

Evaluating the Bacteria Profile and Drug Susceptibility Patterns of Urinary Tract Infectious Pathogens in Pregnant Women in Abakaliki Metropolis, Nigeria

Perpertua Uzoamaka Ekuma, Francis Amadi Ibiam, Moses Ikenna Ekuma, Chidinma Stacy Iroha, Ikemesit Udeme Peter, Ifeanyichukwu Romanus Iroha

International Journal of Pathogen Research · pp. 52–62 · Published 26 Sep 2023

10.9734/ijpr/2023/v12i5243

Abstract

Patient’s demographic data were obtained from a well-structured questionnaire administered before sample collection. A total of two hundred (200) early morning mid-stream urine samples were collected from pregnant women attending Mile 4 hospital to determine the prevalence of UTIs among pregnant women. The collected samples were analysis using Standard Microbiology protocol for isolation and identification of uropathogens. Antibiogram studies of uropathogens were determined using the Kirby–Bauer disk diffusion method and the results were analyzed and were compared with the Clinical Laboratory Standard Institute (CLSI) zone diameter breakpoints. Results of isolation and characterization revealed an overall occurrence rate of 68(34.0%) bacteria consisting of a high distribution of E. coli 27(13.5%) followed by S. aureus 22 (11.0%) and Klebsiella pneumoniae 19 (9.5%). Socio-demographic data of patients revealed that those aged 42-49 years had a high frequency of bacteria 7(70.0%) followed by those aged 34-41 years 50.0%, 18-25 years 31.1% while those aged 26-33 year had the least isolation rate of 26.3%. The occurrence of UTI was highly predominant among patients with no formal level of Education 24(64.9%) than those with formal level of education 17(26.9%). The result of antibiogram studies shows that the isolates exhibited a high percentage of resistance to colistin 100%, azetronam 100% clindamycin 100%, and tetracycline 77.3% but were 92.6%-100% susceptible to cefoxitin, imipenem and amikacin. However, with substantial evidence in this study, cefoxitin, imipenem, and amikacin as drugs of choice could be used for the treatment of UTI, and further studies should be conducted by using highly sensitive and specific techniques such as Polymerase Chain Reaction (PCR), which is the technique used to make numerous copies of a specific segment of the deoxyribonucleic acid quickly and accurately, including genotypic characterization of resistant determinant in bacteria causing UTI among pregnant patients in a larger sample size.

Pregnant women urinary tract infections susceptibility bacteria

References (35)

  1. 1 Origins and virulence mechanisms of uropathogenic Escherichia coli [DOI]
  2. 2 Adhesion and entry of uropathogenic Escherichia coli [DOI]
  3. 3 Prevalence of Bacterial Urinary Tract Infections and Associated Factors among Patients Attending Hospitals in Bushenyi District, Uganda [DOI]
  4. 4 Bacterial profile and drug susceptibility pattern of urinary tract infection in pregnant women at University of Gondar Teaching Hospital, Northwest Ethiopia [DOI]
  5. 5 Distribution and Antimicrobial Susceptibility Pattern of Bacterial Pathogens Causing Urinary Tract Infection in Urban Community of Meerut City, India [DOI]
  6. 6 Antibiotic resistance pattern of community acquired uropathogens at a tertiary care hospital in Jaipur, Rajasthan [DOI]
  7. 7 The burden of antimicrobial resistance among urinary tract isolates of Escherichia coli in the United States in 2017 [DOI]
  8. 8 Prevalence and antibiotic susceptibility of Uropathogens from cases of urinary tract infections (UTI) in Shashemene referral hospital, Ethiopia [DOI]
  9. 9 A nosocomial outbreak of KPC-2-producing Klebsiella pneumoniae in a Chinese hospital: dissemination of ST11 and emergence of ST37, ST392 and ST395 [DOI]
  10. 10 A review of 40 years of enteric antimicrobial resistance research in Eastern Africa: what can be done better? [DOI]
  11. 11 Urinary Tract Infection Etiological Profiles and Antibiotic Resistance Patterns Varied Among Different Age Categories: A Retrospective Study From a Tertiary General Hospital During a 12-Year Period [DOI]
  12. 12 Recurrent Urinary Tract Infections in Women: Risk Factors, Etiology, Pathogenesis and Prophylaxis [DOI]
  13. 13 Antimicrobial Resistance in Bacterial Pathogens and Detection of Carbapenemases in Klebsiella pneumoniae Isolates from Hospital Wastewater [DOI]
  14. 14 Bacterial profile and antibiotic susceptibility pattern of uropathogens causing urinary tract infection in the eastern part of Northern India [DOI]
  15. 15 Incidence of urinary tract infection (UTI) among pregnant women in Ibadan, South-Western Nigeria. [DOI]
  16. 16 Causative agents of urinary tract infections and their antimicrobial susceptibility patterns at a referral center in Western India: An audit to help clinicians prevent antibiotic misuse [DOI]
  17. 17 Extensive antibiotic prescription rate among hospitalized patients in Uganda: but with frequent missed-dose days [DOI]
  18. 18 Prevalence and antimicrobial susceptibility pattern of urinary tract infection among pregnant women attending Hargeisa Group Hospital, Hargeisa, Somaliland [DOI]
  19. 19 Antimicrobial resistance patterns of Uropathogens isolated from adult women with acute uncomplicated cystitis [DOI]
  20. 20 Antimicrobial Susceptibility Patterns of Escherichia coli among Tunisian Outpatients with Community-Acquired Urinary Tract Infection (2012-2018) [DOI]
  21. 21 Bacteriological profile of urinary tract infections and antibiotic susceptibility of Escherichia coli in Algeria [DOI]
  22. 22 Bacterial Profiles and Their Associated Factors of Urinary Tract Infection and Detection of Extended Spectrum Beta-Lactamase Producing Gram-Negative Uropathogens Among Patients with Diabetes Mellitus at Dessie Referral Hospital, Northeastern Ethiopia [DOI]
  23. 23 Prevalence of and factors associated with atypical presentation in bacteremic urinary tract infection [DOI]
  24. 24 Urinary tract infection and Diabetes Mellitus—Etio-clinical profile and antibiogram [DOI]
  25. 25 Trends in Antimicrobial Susceptibility of Escherichia coli Isolates in a Taiwanese Child Cohort with Urinary Tract Infections between 2004 and 2018 [DOI]
  26. 26 Urinary Tract Infection and Antimicrobial Susceptibility of Bacterial Isolates in Saint Joseph Kitgum Hospital, Kitgum, Uganda [DOI]
  27. 27 Emergence of a Klebsiella pneumoniae ST392 clone harbouring KPC-3 in an Italian transplantation hospital [DOI]
  28. 28 A survey on urinary tract infection associated with two most common uropathogenic bacteria [DOI]
  29. 29 Prevalence and Antbiogram of Bacterial Isolates Causing Urinary Tract Infections at Federal Teaching Hospital Abakaliki I (FETHA I) [DOI]
  30. 30 Bacterial and antibiotic susceptibility pattern of urinary tract infection isolated from asymptomatic and symptomatic diabetic patients attending tertiary hospital in Jos, Nigeria [DOI]
  31. 31 Identification and Antibiotic Resistance Profile of Biofilm-forming Methicillin Resistant Staphylococcus aureus (MRSA) Causing Infection among Orthopedic Wound Patients [DOI]
  32. 32 Methicillin-Resistant [DOI]
  33. 33 [Hospital-acquired urinary tract infections].
  34. 34 Bacterial profile, antibiotic susceptibility pattern and associated risk factors of urinary tract infection among clinically suspected children attending at Felege-Hiwot Comprehensive and Specialized Hospital, Northwest Ethiopia. A prospective study [DOI]
  35. 35 Prevalence and Antimicrobial Susceptibility Pattern of Urinary Tract Infection among Pregnant Women Attending Hargeisa Group Hospital, Hargeisa, Somaliland [DOI]

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