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Research Article Open access CC BY 4.0

Vanishing Bile Duct Syndrome Mini-review and Case Report of This Rare Disease

Cohen Ramon, Attali Malka

Asian Journal of Case Reports in Medicine and Health · pp. 127–133 · Published 19 Jul 2023

Abstract

Aim: Vanishing bile duct syndrome (VBDS) is a rare condition that affects the liver and bile ducts. It is characterized by the progressive destruction or loss of bile ducts in the liver. The causes of vanishing bile duct syndrome are not fully understood, but it can occur as a result of a variety of factors, including infections, autoimmune disorders, certain medications, and genetic conditions. Presentation: we report a case of VBDS after a treatment with Bortezumid and Linelomide. We explain the pathophysiology and the actual knowledge of the treatment. Conclusion: Plasmapheresis not seems to replace immunosuppressive treatment if there are not improvement and support that the use of plasmapheresis in isolated VBDS is limited.

Dili Drug induce liver injury VBDS vanishing bile duct syndrome multiple myeloma

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