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Research Article Open access CC BY 4.0

Efficacy and Safety of Photobiomodulation on Non-infected Pressure Ulcer in Adults: A Study Protocol of Randomized Clinical Trials

Adriana da Silva Magalhães, Lara Jansiski Motta, Isabel Veloso Alves Pereira, Sandra Kalil Bussadori, Cinthya Cosme Gutierrez Duran, Kristianne Porta Santos Fernandes, Raquel Agnelli Mesquita-Ferrari, Anna Carolina Ratto Tempestini Horliana

Journal of Advances in Medicine and Medical Research · pp. 212–218 · Published 14 Dec 2024

10.9734/jammr/2024/v36i125668

Abstract

Pressure injuries (PIs) are a significant public health issue, causing harm and compromising the safety of hospitalized patients. Some studies suggest that photobiomodulation may promote anti-inflammatory effects and wound revascularization, accelerating the healing process in skin wounds. However, the quality of evidence remains limited. Objective: To evaluate the effectiveness and safety of photobiomodulation as a treatment for non-infected PIs in adults. Methods: It followed the methodological guidelines of the Cochrane Handbook for Systematic Reviews of Interventions and the PRISMA Statement. A systematic search for randomized controlled trials (RCTs) will be conducted in databases from their inception to December 2024 without language restrictions. The databases included MEDLINE, EMBASE, CENTRAL, LILACS, BBO, ICTRP, ClinicalTrials.gov, WHO, and OpenGrey. PROSPERO Registration Number: CRD42020200637.

Systematic review pressure injury photobiomodulation wound healing

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