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Effects of Gravidity on Atherogenic Indices in Normotensive and Hypertensive Second Trimester Pregnant Women

Oladapo-Akinfolarin Tomaziga Tomiloba, Akinfolarin Oladapo Mayowa, Ken-Ezihuo Stella Urekweru, Anyalebechi Eberechukwu Okwuchi

Journal of Advances in Biology & Biotechnology · pp. 50–57 · Published 27 Jul 2022

10.9734/jabb/2022/v25i430278

Abstract

Background: Pregnancy results in certain physiological and metabolic changes that results to shift in certain biochemical markers and could even result in hypertension in some women thus predisposing them to risk of cardiovascular disease. While this is true, some women express these predisposing risk factors in subsequent pregnancies. Therefore, it may be a significant contribution to understand the dynamics of artherogenic indices with increasing number of pregnancies. Aim: The goal of the study was aimed to assess gravidity effect on artherogenic indices in both normotensive and hypertensive second-trimester pregnant women. Materials and Methods: At Rivers State University Teaching Hospital, a cross-sectional study was carried out with 100 pregnant women. The consenting patients who met the inclusion criteria were classified into two groups: normotensive (50 normotensive pregnant women in their second trimester) and hypertensive (50 hypertensive pregnant women in their second trimester) (HPW2T). The participants were subsequently split into three subgroups depending on gravidity: primigravida (no of pregnancy=1), multigravida (no of pregnancies>1), and grand multigravida (no of pregnancies≥5). For the assessment of TC, TG, HDL, and LDL, fasting blood samples were taken using the venepuncture technique. Mathematically, artheriogenic indices (AIP, CR-I, CR-II, AC, and APoB/APoA1) were calculated. At a P-value>0.05, the data was examined using ANOVA and the Tukey comparison test. Results: There was no significant difference in artheriogenic indices between the gravidity groups in the normotensive group, with a P-value>0.05, which was also the cases among those in the hypertensive group. Conclusion: The study has shown that gravidity does not have any effect on artheriogenic indices among normotensive and hypertensive pregnant women in the second trimester in Rivers State University Teaching Hospital.

Normotensive hypertensive artheriogenic pregnancy second trimester

References (21)

  1. 1 Estimation of the Concentration of Low-Density Lipoprotein Cholesterol in Plasma, Without Use of the Preparative Ultracentrifuge [DOI]
  2. 2 Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies [DOI]
  3. 3 Enzymatic Determination of Total Serum Cholesterol [DOI]
  4. 4 Lipoprotein ratios: Physiological significance and clinical usefulness in cardiovascular prevention [DOI]
  5. 5 Pathological aspects of lipid peroxidation [DOI]
  6. 6 Cholesterol esterification and atherogenic index of plasma correlate with lipoprotein size and findings on coronary angiography [DOI]
  7. 7 Impairment of endothelial function in women with a history of preeclampsia: an indicator of cardiovascular risk [DOI]
  8. 8 Cardiovascular and Cerebrovascular Disease Associated microRNAs Are Dysregulated in Placental Tissues Affected with Gestational Hypertension, Preeclampsia and Intrauterine Growth Restriction [DOI]
  9. 9 Can antenatal clinical and biochemical markers predict the development of severe preeclampsia? [DOI]
  10. 10 Involvement of Galectin-9/TIM-3 Pathway in the Systemic Inflammatory Response in Early-Onset Preeclampsia [DOI]
  11. 11 Lipid profile, plasma apolipoproteins, and pre-eclampsia risk in the GenPE case-control study [DOI]
  12. 12 A Study on Atherogenic Indices of Pregnancy Induced Hypertension Patients as Compared to Normal Pregnant Women [DOI]
  13. 13 Evaluation of Nutrient Composition in Breast Milk of Breast Feeding Mothers in Urban and Sub-Urban Subjects in Rivers State [DOI]
  14. 14 Comparative Study of Heavy Metals in Breast Milk of Breast Feeding Mothers in Urban and Sub-Urban Subjects in Rivers State [DOI]
  15. 15 Assessment of colorimetric enzymatic determination of triglyceride, by manual and centrifugal analyzer techniques, and comparison with a CDC standardized method [DOI]
  16. 16 Regulating intestinal function to reduce atherogenic lipoproteins [DOI]
  17. 17 Study of atherogenic indices in nephrotic syndrome
  18. 18 Biochemical Markers of Atherosclerosis [DOI]
  19. 19 Changes in Endothelial Function Precede the Clinical Disease in Women in Whom Preeclampsia Develops [DOI]
  20. 20 ATHEROGENIC PARAMETERS AND CARDIAC INDICES IN PROGNOSTICATION OF DEVELOPMENT OF PRE-ECLAMPSIA AND ITS CARDIOMETABOLIC CONSEQUENCES [DOI]
  21. 21 JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH [DOI]

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