Effects of Canned Tomatoes Consumption on Hematological Profile, Renal Markers, and Histology Using Male Wistar Rats

Abstract

Background: Tomatoes are currently an important food component globally, they are the largest vegetable both in terms of production and consumption. This study was aimed at investigating the effect of tomato consumption on hematological parameters, renal markers, and renal histology of male Wistar rats. Methods: A study involved 20 male Wistar rats and 30 pieces of Gino tomato paste. The rats were acclimatized for 14 days and divided into two groups. The experiment was carried out in two phases, with the experimental group fed tomato paste and water. After each phase, samples were collected for hematological and biochemical analysis. Results: The results from the hematological analysis show that Packed Cell Volume, Hemoglobin, and Red Blood Cells were significant in the acute phase while they were not in the recuperation phase. The Biochemical analysis shows Potassium and Chloride (Cl-) as not significant although potassium levels were found to be very high in the acute phase while none of the biochemical parameters were found to be significant in the recuperation phase. Histologically there were no observed pathological changes of the normal kidney against the kidney of tomato administer rats. Conclusion: The study shows that consumption of tomato paste affects renal maker Potassium as it increases its normal level. It further shows that consuming tomato paste increases the Hemoglobin, Pack Cell Volume, and Red Blood Cells.