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Research Article Open access CC BY 4.0

Determining the Glycemic Index of Nutritional Product for Diabetes Mellitus- Np through Measuring Glycemic Responses to Reference Food (Glucose) and Test Food (Nutritional product -Np)

Nguyen Thi Diep Anh, Nguyen Trong Hung, Tran Thi Tra Phuong, Le Thi Hang, Dinh Tran Ngoc Huy, Vu Thi Thu Hien, Bui Thi Thuy, Ngo Thi Thu Huyen, Le Thi Tuyet Nhung, Nguyen Thi Luong Hanh, Tu Thi Mai, Truong Tuyet Mai, Nguyen Hong Truong, Le Danh Tuyen

Journal of Pharmaceutical Research International · pp. 298–307 · Published 2 Nov 2021

10.9734/jpri/2021/v33i47B33128

Abstract

The objective was to determine the glycemic index (GI) of Nutritional product for Diabetes Mellitus through measuring glycemic responses to reference food (Glucose) and test among nutritional product 13 participants. The study was a self-controlled clinical trial with 13 qualified participants (8 men and 5 women). They were required to go through the study protocol with reference food and test food. For each individual, seven blood samples were taken in the fasting state and at 15, 30, 45, 60, 90 and 120 minutes after ingestion. Our results show that at all measurement points, the blood glucose levels after consumption of test food were lower than after consumption of reference food. The incremental area under the curve (iAUC) and a GI value of Nutritional product (NP) were calculated for each meal. Mean ± SD of GI value was calculated for test food for the combined group of subjects. Mean iAUC and GI value of Nutritional product were 62,1 ± 12,5 mmol·min/L and 44,9 ± 7,2, significantly lower to those of reference food, which were 132,6 ± 14,8 mmol·min/L and 100, respectively. Finding from the study demonstrated that Nutritional product (GI = 44,9) would be classified as a low – GI food.

Clinical trial glycemic index nutritional product national institute of nutrition

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