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Research Article Open access CC BY 4.0

Dengue and Chikungunya Coinfection Associated with Multi Organ Dysfunction Syndrome and Ttp: A Case Report

Likitha B S, Brunda M S, Praveen Kumar, Rohith A, Santosh M

International Journal of Medical and Pharmaceutical Case Reports · pp. 66–73 · Published 28 Dec 2024

10.9734/ijmpcr/2024/v17i4404

Abstract

Aim: Dengue (DENV) and chikungunya (CHIKV) fever are the two serious arboviral diseases presenting as self-limiting acute febrile illness reporting over 1,00,000 cases in a year. Dengue and chikungunya fever can transmit through the same vector and share similar symptoms, ruling out the diagnosis and its timely management could be time consuming. Presentation of Case: Here we discuss a case of dengue and chikungunya coinfection associated with Thrombotic Thrombocytopenic Purpura (TTP) in an adult Indian female presented with acute febrile illness that later on progressed to Multi Organ Dysfunction Syndrome affecting brain, kidney, lungs and haematological system. Discussion and Conclusion: We discuss the diagnostic approaches, management of this complicated case and would like to generate an awareness regarding the coinfection of these viruses, their complications leading to multiorgan damage.

Dengue fever thrombocytopenia chikungunya virus thrombotic thrombocytopenic purpura multi organ dysfunction syndrome coinfection

References (9)

  1. 1 Pathophysiology of chikungunya virus infection associated with fatal outcomes [DOI]
  2. 2 Clinical outcomes of chikungunya: A systematic literature review and meta-analysis [DOI]
  3. 3 Global prevalence of dengue and chikungunya coinfection: A systematic review and meta-analysis of 43,341 participants [DOI]
  4. 4 Dengue Mimickers: Which Clinical Conditions Can Resemble Dengue Fever? [DOI]
  5. 5 Coinfection of chikungunya and dengue viruses: A serological study from North Western region of Punjab, India [DOI]
  6. 6 Comodulation of Dengue and Chikungunya Virus Infection During a Coinfection Scenario in Human Cell Lines [DOI]
  7. 7 Competitive suppression of dengue virus replication occurs in chikungunya and dengue co-infected Mexican infants [DOI]
  8. 8 Dengue fever presenting as thrombotic thrombocytopenic purpura in adolescent girl: A case report [DOI]
  9. 9 A Rare Intersection: Managing Thrombotic Thrombocytopenic Purpura in the Context of Dengue Fever [DOI]

Cited by 2

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