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Comprehensive Geriatric Assessment and Its Clinical Correlates among Hospitalized Older Adults in the Brazilian Amazon: A Descriptive Cohort Study

Isabela Dourado de Carvalho, Laryssa Trindade, Laiane Moraes Dias, Adonias Brito dos Santos Júnior, Camila Miranda Pereira, Natália De Almeida Façanha, Rudival Faial De Moraes Júnior, Gabriela Ladeia da Silva, Yuri De Sousa Azevedo, Raissa Barbosa De Arêde, Daniel Oliveira Kato, Valdenira de Jesus Oliveira Kato, Ana Paula Sabado Feio, Jefferson Lazarini de Aquino, Paulo Lucas Paes Duarte, Matheus Moreira de Melo

International Neuropsychiatric Disease Journal · pp. 161–172 · Published 29 Oct 2025

10.9734/indj/2025/v22i5523

Abstract

Aims: This study aimed to evaluate the functional, clinical, and cognitive profiles of hospitalized older adults in a general hospital in the Brazilian Amazon, contributing to understanding the relationship between frailty, cognitive decline, and functionality during hospitalization. Study Design: Prospective and analytical cohort study. Place and Duration of Study: Conducted at Hospital Jean Bitar, Belém, Pará, Brazil, from March to June 2023. Methodology: The study included 45 patients aged 65 years or older, assessed within 48 hours of admission using validated instruments such as the Clinical Frailty Scale (CFS), 10-Point Cognitive Screener (10-CS), Katz Index for Basic Activities of Daily Living (BADL), and Lawton Scale for Instrumental Activities of Daily Living (IADL). Statistical analyses were performed using BioEstat® 5.4, applying G and Chi-Square tests (α = 0.05). Results: The mean age was 76.3 years, with a slight predominance of females (51.1%, p = 0.8815). The most frequent admission diagnoses were gastrointestinal bleeding (24.4%) and consumptive syndrome (22.2%). A statistically significant association was found between sex and cognitive impairment (p = 0.0030; Cramer’s V = 0.42), with females showing a higher prevalence of probable cognitive impairment (73.9%). The 10-CS revealed a significant difference across cognitive categories (p = 0.0006; V = 0.51). The CFS demonstrated a significant association with mortality risk (p = 0.0282), where higher frailty scores correlated with greater mortality probability. Conclusion: Functional dependence and cognitive decline were prevalent among hospitalized older adults, particularly among females, with significant associations between frailty, cognition, and mortality. These findings reinforce the need for comprehensive geriatric assessments to guide care strategies and improve quality of life in this population.

Older adults frailty cognitive impairment functional dependence

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