Complications of Diabetes: Cardiovascular, Renal, and Neurological Implications
Mohamed Aboelmaaty, Huseyin Erdem AK, Nithish Gaddam, Mehwish Aqueel, Masood Ahmed, Muhammad Sohail S. Mirza, Kholood Ahmed
Journal of Advances in Medicine and Medical Research · pp. 103–112 · Published 10 Jun 2025
10.9734/jammr/2025/v37i65855Abstract
Diabetes mellitus poses significant health challenges primarily due to its severe complications affecting the cardiovascular, renal, and nervous systems. Chronic hyperglycemia drives these complications through mechanisms like oxidative stress, inflammation, and the formation of advanced glycation end products, manifesting as both microvascular and macrovascular damage. Cardiovascular complications, including stroke and coronary artery disease, represent the leading cause of mortality among diabetic patients. Renal involvement leads to diabetic nephropathy, characterized by kidney damage. Furthermore, metabolic and vascular disturbances cause neurological complications, notably diabetic neuropathy. Effective prevention and management of these complications rely on stringent blood glucose control, alongside lifestyle modifications and pharmacological interventions.
Cited by 2
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