Comparison of the Effect of Pregabaline and Diclofenac Suppository on Pain Relief after Elective Cesarean Section
Asadollah Shakeri, Maryam Razavi, Zeinab Mirkahnuj
Journal of Pharmaceutical Research International · pp. 1–6 · Published 21 Dec 2019
10.9734/jpri/2019/v31i630355Abstract
Introduction: Cesarean section is one of the most common major surgeries performed worldwide. Considering the importance of post-cesarean pain, finding a drug that can provide the patient with the least amount of complications can make the patient feel the least pain and most relaxation. The aim of this study was to compare the effect of pregabaline and diclofenac suppository on pain relief after elective cesarean section with spinal anesthesia. Methods: This study was performed in 2016 on 100 women admitted to Ali Ibn Abi Talib Hospital due to elective cesarean section. Patients were divided into two groups of 100mg rectal diclofenac half an hour before surgery and 300mg pre-gabbaline group. Data were analyzed using SPSS software. Probability level lower than 0.05 was considered significant. Results: The mean score of after surgery pain at 6 and 12 hours after surgery in the diclofenac group was significantly lower than in the pregabaline group, but at 18 and 24 hours, the difference between the two groups was not statistically significant. The mean dose of pethidine used in the diclofenac group was significantly lower than the pregabaline group. Maternal satisfaction was significantly higher in the diclofenac group. Conclusion: According to the results of this study, diclofenac has a stronger antinociceptive effect than pregabalin.
References (10)
- 1 Preemptive Analgesia—Treating Postoperative Pain by Preventing the Establishment of Central Sensitization [DOI]
- 2 Pregabalin: Its Pharmacology and Use in Pain Management [DOI]
- 3 Preemptive analgesia I: physiological pathways and pharmacological modalities [DOI]
- 4 The Prevalence of Postoperative Pain in a Cross-sectional Group of Patients After Day-case Surgery in a University Hospital [DOI]
- 5 Oral analgesia in the treatment of post-cesarean pain [DOI]
- 6 Comparison of pregabalin versus ketamine in postoperative pain management in breast cancer surgery [DOI]
- 7 Comparison of Diclofenac with Pethidine on the Pain after Cesarean Section [DOI]
- 8 THE EFFECT OF TRANSVERSUS ABDOMINIS PLANE (TAP) BLOCK WITH BUPIVACAINE 25% ON POST CESAREAN PAIN
- 9 Comparison of Low Dose Gabapentin and Diclofenac Efficacy for Postoperative Pain Reduction after Abdominal Hysterectomy: a Randomized Clinical Trial
- 10 The Effect of Rectal Diclofenac in Post-Cesarean Analgesia and Reducing the Patients Opioid Sedative Needs
Cited by 1
M. Ahmad, Rezki Hardiyanti Taufik · Jurnal Anestesi Obstetri Indonesia · 2021
Related research
- Parecoxib, Dezocine and Epidural Morphine for Perioperative Multimodal Analgesia in Cesarean Section: A Randomized Study — shares topic coverage
- Tranexamic Acid as Prophylactic Therapy for Intra and Post Partum Hemorrhage, Randomized Controlled Trial — shares topic coverage
- Relationship between Premature Rupture of the Membrane and Cesarean Delivery: Case from Jakarta, Indonesia — shares topic coverage
- Knowledge, Attitudes, and Perceptions of Cesarean Section among Women in Delta State, Nigeria: Implications for Maternal Health Interventions — shares topic coverage
- Cesarean Section Rates and Indications in Turkey: A Systematic Review and Meta-Analysis — shares topic coverage
Article metrics
Real usage data collected on this platform.
13
Page views
0
PDF downloads
0
Outbound clicks
1
Citations
Views over time
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
Traffic sources
Referring site, by host.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.