Clinico-Pathological Findings of Transitional Cell Carcinoma in a Beagle Dog: A Case Report

Abstract

An 11 year old male beagle dog was presented to the Department of Veterinary Surgery and Radiology, Institute of Veterinary Science and Animal Husbandry, SOA (Deemed to be University) with a history of stranguria, pollakiuria and hematuria since 1 month. Survey radiography was performed and pneumocystography was done by infusing air via a sterile urinary catheter. After removal of the catheter, a biopsy sample of the intraluminal mass to the tip of the catheter was subjected to cytological examination. A urine sample was also collected after aseptic catheterization of the bladder and a direct wet mount examination was performed. A Giemsa stained smear was prepared from the mass, air dried and fixed with methanol. Radiograph of the abdomen showed a mildly distended urinary bladder with soft tissue opacity within the lumen of the bladder. Cytological examination revealed presence of cluster of round to polygonal transitional epithelial cells exhibiting marked pleomorphism with anisocytosis and anisokaryosis. The early detection of transitional cell carcinoma plays a pivotal role in guiding appropriate treatment strategies, slowing disease progression and improving pet survival and quality of life.