Budleja asiatica Derived Phytochemicals against Eye Disease
Sarthak Siddhant Mishra, Sasmita Patra, Bhakti Bhusan Das, Dipankar Bhattacharyay, Mukundjee Pandey
Journal of Pharmaceutical Research International · pp. 120–123 · Published 25 May 2020
10.9734/jpri/2020/v32i730521Abstract
The secondary metabolites in the plants are the reason for curing various diseases. And the phytochemicals present in Budleja asiatica plant extract can cure Eye disease which is caused by Haemophilus influenzae is a facultatively anaerobic, gram-negative pathogenic bacteria. For analysis of ligand-protein interaction, the molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that lignoceric acid can effectively deactivate Aspararte semialdehyde dehydrogenase enzyme which is important macromolecule for the regulation of amino acid biosynthesis resulting in interrupting the life cycle of the microorganism.
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