Buddleja asiatica Derived Phytochemicals against Diarrhea
Journal of Pharmaceutical Research International · pp. 124–127 · Published 15 May 2020
10.9734/jpri/2020/v32i630506Abstract
Plants produce nonnutritive compounds that are often extracted to make herbal medicines. It has been reported that extracts of Buddleja asiatica are effective to treat diarrhea. One of the causes of Diarrhea is an infection by Campylobacter jejuni. The objective of the study is to identify the phytochemical of Buddleja asiatica capable of curing Diarrhea. ATP-phosphoribosyl transferase enzyme plays an important role in Purine Metabolism. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that Lignoceric acid can effectively deactivate the transferase enzyme thereby interrupting the life cycle of the organism.
Cited by 1
Alicia Monserrat Vazquez-Marquez, José Correa-Basurto, Víctor Varela-Guerrero · Future Journal of Pharmaceutical Sciences · 2024
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