Skip to content
Research Article Open access CC BY 4.0

BisGMA and TEGDMA Elution from Two Flowable Nanohybrid Resin Composites: An In vitro Study

Mithra N. Hegde, Ankita Wali

Journal of Advances in Medicine and Medical Research · pp. 1096–1104 · Published 29 Oct 2014

10.9734/BJMMR/2015/12951

Abstract

Aim: The aim of our study was to evaluate the amount of release of BisGMA and TEGDMA from two commercially available enamel replacement composites; Tetric N-Flow™ and G-aenial Universal Flo™ over a period of 24 hours after polymerization with a standard LED Curing Unit. Methods and Materials: Two flowable nanohybrid composite materials; Tetric N-Flow™ (Ivoclar Vivadent AG, Liechtenstein) and G-aenial Universal Flo™ (GC, India) were investigated and grouped into two groups. Ten samples from each group were prepared by inserting the material into a standardized Teflon mould of size 2x2x2 mm. Each sample was cured with a LED curing unit for 20 seconds and was stored in 2 ml of Ethanol at room temperature. After 24 hours, the samples were removed from the storage medium (ethanol) and prepared for measurements. A reverse phase HPLC unit was used to detect the release of BisGMA and TEGDMA monomers from the prepared samples. The acquired measurements were obtained after testing them in a High Liquid Performance Chromatography Unit. The data obtained was statistically analyzed and the results revealed significant amount of release of TEGDMA as well as BisGMA. Results: G-aenial Universal Flo™ showed significant release of both TEGDMA as well as BisGMA as compared to Tetric N- Flow™. The increase was by 0.5 units. Conclusion: Significant amount of release of TEGDMA as well as BisGMA was seen in both the composite materials after HPLC Unit analysis. This can help in the evaluation of cytoxicity to the soft tissues in the oral environment.

BisGMA flowable composites HPLC unit monomer elution TEGDMA.

References (33)

  1. 1 Hygroscopic and hydrolytic effects in dental polymer networks [DOI]
  2. 2 Systematic review of the chemical composition of contemporary dental adhesives [DOI]
  3. 3 Estrogenicity of Resin-Based Composites and Sealants Used in Dentistry [DOI]
  4. 4 Effect of light intensity and exposure duration on cure of resin composite.
  5. 5 The Effect of Oxygen Inhibition on an Unfilled/Filled Composite System [DOI]
  6. 6 Substances released from dental resin composites and glass ionomer cements [DOI]
  7. 7 Dental composite depth of cure with halogen and blue light emitting diode technology [DOI]
  8. 8 Rate of elution of leachable components from composite [DOI]
  9. 9 Elution study of unreacted Bis‐GMA, TEGDMA, UDMA, and Bis‐EMA from light‐cured dental resins and resin composites using HPLC [DOI]
  10. 10 Future perspectives of resin-based dental materials [DOI]
  11. 11 Resin composite monomers alter MTT and LDH activity of human gingival fibroblasts in vitro [DOI]
  12. 12 In vitro cytotoxicity and dentin permeability of HEMA [DOI]
  13. 13 Long‐term release of monomers from modern dental‐composite materials [DOI]
  14. 14 Elution of monomers from two conventional dental composite materials [DOI]
  15. 15 Influence of Chemicals on Wear of Dental Composites [DOI]
  16. 16 Correlation of cytotoxicity, filler loading and curing time of dental composites [DOI]
  17. 17 A comparison of polymerization by light-emitting diode and halogen-based light-curing units [DOI]
  18. 18 Unpolymerized Surface Layers on Sealants [DOI]
  19. 19 Components of Dentinal Adhesives Modulate Heat Shock Protein 72 Expression in Heat-stressed THP-1 Human Monocytes at Sublethal Concentrations [DOI]
  20. 20 Pattern of cell death after in vitro exposure to GDMA, TEGDMA, HEMA and two compomer extracts [DOI]
  21. 21 Effects of three resin monomers on the cellular glutathione concentration of cultured human gingival fibroblasts [DOI]
  22. 22 The effect of BisGMA on cyclooxygenase-2 expression, PGE2 production and cytotoxicity via reactive oxygen species- and MEK/ERK-dependent and -independent pathways [DOI]
  23. 23 Release of monomers from different core build-up materials [DOI]
  24. 24 Monomer Release from Resin Based Dental Materials Cured With LED and Halogen Lights [DOI]
  25. 25 Toxicity potentiation by H2O2 with components of dental restorative materials on human oral cells [DOI]
  26. 26 Extent of Polymerization of Dental Resins by Differential Scanning Calorimetry [DOI]
  27. 27 Materials Science [DOI]
  28. 28 Biocompatibility of composite resins. [DOI]
  29. 29 A calorimetric study of the interaction of synthetic phospholipid liposomes with lipid‐soluble small molecules used as dental materials and devices [DOI]
  30. 30 High-performance liquid chromatographic determination of unreacted monomers and other residues contained in dental composites [DOI]
  31. 31 Genotoxicity evaluation of dental restoration nanocomposite using comet assay and chromosome aberration test [DOI]
  32. 32 An evaluation of four light-curing units comparing soft and hard curing.
  33. 33 [The application of fluorinated aromatic dimethacrylates and diacrylates to light-cured composite resins. 1. Improvement of transmittance of composite].

Cited by 13

Akıcı Kompozitler: Bir Literatür Derlemesi

Muhammet FİDAN, Zeynep DERELİ · Selcuk Dental Journal · 2021

Effects of nanohybrid flowable resin‐based composites on fibroblast viability using different light‐curing units

Dalea M. Bukhary, Afnan O. Al‐Zain, Ruwaida Z. Alshali · Journal of Prosthodontics · 2022

Comparative evaluation of three nanofilled resin-based dental composites: Cytotoxicity, surface roughness, and flexural properties

Shiva Jafarnia, Alireza Valanezhad, Tetsurou Odatsu · Polymers and Polymer Composites · 2022

In-vivo Biocompatibility Evaluation of Different Self-Adhering Composite Resins on Wister Rats

Ayşegül Saygin, Murat Ünal, Tülay Koç · Journal of Photopolymer Science and Technology · 2021

Transiting Milestones in Conventional Composites: A Headway for Flowables

Mrinal Nadgouda, Aditya Patel, Pradnya Nikhade · Journal of Datta Meghe Institute of Medical Sciences University · 2023

Showing 6 of 13 known citations — external sources report more than can currently be individually listed.

Article metrics

Real usage data collected on this platform.

65

Page views

0

PDF downloads

20

Outbound clicks

13

Citations

Views over time

Views by country

Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".

Traffic sources

Referring site, by host.

Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.