Chromosomal Abnormalities with Recurrent Miscarriage in Couples (A Clinical Study)

Abstract

The study demonstrated as a cytogenetic study which carried out in Baghdad Governorate on 40 couples have a history of more than 3 recurrent miscarriages, their ages ranged from 20-39 years old for females and 30- 42 years old for males , they came to the ANSEJA medical laboratories in Baghdad for Karyotyping testing . Identifying the shape and structure of the blood couples chromosome using MetaClass Karyotyping system. The result show that : nine cases were found to have abnormal structure of chromosome anomalies while the other 31 cases had a normal Chromosomal complement 5 cases of the tested samples had been show a marker chromosome (47,XX,+mar) , 3 cases of the tested samples show ring chromosome that found in mosaicism (46, XX/47, XX, +r) and the last 2 case was father with Klinefelter syndrome (47,XXY). The study conclude that the chromosomal abnormalities can be possibly evaluated in the patient ,with the history of recurrent spontaneous miscarriage, using conventional cytogenetic detection.