Skip to content
Research Article Open access CC BY 4.0

Assessment of Antimicrobial Activities of Some Selected Medicinal Plants Used in the Treatment of Skin and Wound Infections in Bauchi Town, Bauchi State Nigeria

Zailani S.B, Shuiabu Y. U., Maryam Adamu Bapha, Mudathir Qossim, Zakari N.D., Lawal A.S, Muhammad L.

European Journal of Medicinal Plants · pp. 42–56 · Published 18 Jul 2024

10.9734/ejmp/2024/v35i41197

Abstract

Aims: This study aimed to capture the medicinal plants used locally to treat skin and wound infection, and to investigate the antimicrobial activity of the ethanol, ethyl acetate, and aqueous extracts of Azadiracta indica, Mitracarpus hirtus, Calotropis procera, and Commiphora africana against bacterial and fungal pathogens causing skin and wound infections. Study Design: This was a cross-sectional analytical study, conducted in Bauchi town from January to April 2024 at the Department of Medical Microbiology, Abubakar Tafawa Balewa University. Methodology: A semi-structured questionnaire was used to gather information on the use of medicinal plants in treating skin and wound diseases. Twelve leaves extracts from Azadirachta indica, Mitracarpus hirtus, Calotropis procera, and Commiphora africana were screened for their antimicrobial activity against four bacterial and one fungal pathogen; Staphylococcus aureus, Proteus mirabilis, Pseudomonas aeruginosa klebsiella pneumonia, Escherichia coli and Trichophyton rubrum using Agar Disc Diffusion Assay. Minimum Inhibitory Concentrations (MIC) was performed using micro broth dilution assay. Results: A total of 94 respondents used 28 medicinal plants for skin and wound disease management, including leaf paste, infusion, root powder, dried powdered leaves, and oral decoction. The most common plants used were Azadirachta indica, Mitracarpus hirtus, Calotropis procera, and Commiphora africana, used to treat eczema, ringworm, skin rashes, and burnt wounds. All of the plant extracts were effective in inhibiting bacterial and fungal growth at variable concentrations, with Mitracarpus hirtus being the most effective. Mitracarpus hirtus showed the greatest zone of inhibition (ZOI >20 mm) against Staphyloccus aureus and Trichophyton rubrum, followed by Calotropis procera, which had moderate activity on the test isolates with a mean ZOI >11mm. Azadirachta indica and Commiphora africana exhibited mild to poor action on the majority of the isolates. For each plant extract, the MIC values differed according to the bacterial species. Mitracarpus hirtus had the lowest MIC against Staphyloccus aureus at 0.325 mg/mL, as did Calotropis procera against Klebsiella  pneumoniae. Conclusion: The study discovered that many medicinal plants had promising antibacterial activities against the tested isolates, but more research is required to identify and purify active components for safe use.

Antimicrobial activity skin wounds medicinal plant Bauchi

References (37)

  1. 1 Towards Advances in Medicinal Plant Antimicrobial Activity: A Review Study on Challenges and Future Perspectives [DOI]
  2. 2 Bioethanol production using carbohydrate-rich microalgae biomass as feedstock [DOI]
  3. 3 Importance of ethnopharmacological studies in drug discovery: role of medicinal plants [DOI]
  4. 4 Traditional Therapies for Skin Wound Healing [DOI]
  5. 5 Ethnomedicinal study of plants used by Sheko ethnic group of Ethiopia [DOI]
  6. 6 Challenges in Healing Wound: Role of Complementary and Alternative Medicine [DOI]
  7. 7 Ethnopharmacological application of medicinal plants to cure skin diseases and in folk cosmetics among the tribal communities of North-West Frontier Province, Pakistan [DOI]
  8. 8 Biofilm-Innate Immune Interface: Contribution to Chronic Wound Formation [DOI]
  9. 9 Medicinal Plants of the World [DOI]
  10. 10 Skin Infections Caused by Staphylococcus aureus [DOI]
  11. 11 Nanocoatings for Chronic Wound Repair—Modulation of Microbial Colonization and Biofilm Formation [DOI]
  12. 12 Antimicrobial Importance of Medicinal Plants in Nigeria [DOI]
  13. 13 Investigations of antimicrobial activity of some Cameroonian medicinal plant extracts against bacteria and yeast with gastrointestinal relevance [DOI]
  14. 14 Microenvironment and microbiology of skin wounds: the role of bacterial biofilms and related factors [DOI]
  15. 15 Antimicrobial activity of apple cider vinegar against Escherichia coli, Staphylococcus aureus and Candida albicans; downregulating cytokine and microbial protein expression [DOI]
  16. 16 Ethnobotany of traditional medicinal plants and associated indigenous knowledge in Dawuro Zone of Southwestern Ethiopia [DOI]
  17. 17 Traditional medicine usage among adult women in Ibadan, Nigeria: a cross-sectional study [DOI]
  18. 18 An ethnobotanical survey of Bauchi State herbal plants and their antimicrobial activity [DOI]
  19. 19 Inflammation and Wound Healing: The Role of Bacteria in the Immuno-Regulation of Wound Healing [DOI]
  20. 20 In Vitro Antibacterial Activity of Selected Medicinal Plants in the Traditional Treatment of Skin and Wound Infections in Eastern Ethiopia [DOI]
  21. 21 Indigenous medicinal plants of Pakistan used to treat skin diseases: a review [DOI]
  22. 22 Medicinal Plants Market and Industry in Africa [DOI]
  23. 23 Health Benefits of Isoflavones Found Exclusively of Plants of the Fabaceae Family [DOI]
  24. 24 Medicinal foods and beverages among Maasai agro-pastoralists in northern Tanzania [DOI]
  25. 25 Moisture-associated skin damage: an overview of its diagnosis and management [DOI]
  26. 26 Descriptive epidemiology of measles cases in Bauchi State, 2013–2018 [DOI]
  27. 27 Geographical Regions of Nigeria [DOI]
  28. 28 Antimicrobial and Phytochemical Screening of Plumbago zeylanica Linn. (Plumbaginaceae) Leaf
  29. 29 Knowledge, Attitude and Practice of Community on Traditional Medicine in Jara Town, Bale Zone South East Ethiopia [DOI]
  30. 30 Pharmacological Evaluation of Selected Medicinal Plants Used in the Management of Oral and Skin Infections in Ebem-Ohafia District, Abia State, Nigeria [DOI]
  31. 31 Pseudomonas aeruginosa as a Powerful Biofilm Producer and Positive Action of Amikacin Against Isolates From Chronic Wounds [DOI]
  32. 32 Ethnopharmacological Study of Medicinal Plants in Bajwat Wildlife Sanctuary, District Sialkot, Punjab Province of Pakistan [DOI]
  33. 33 American Indian Health: Integrating Traditional Native Healing Practices and Western Medicine [DOI]
  34. 34 Surveillance of multidrug resistant suppurative infection causing bacteria in hospitalized patients in an Indian tertiary care hospital [DOI]
  35. 35 Antibacterial Activity of Alkaloid, Flavonoids and Lipids from Crude Extracts of Azadirachta indica on Some Selected Medically Important Bacteria [DOI]
  36. 36 The Impact of Climate Change on Skin and Skin-Related Disease [DOI]
  37. 37 Plant Diversity in Western Ethiopia : Ecology, Ethnobotany and Conservation

Cited by 4

Potential of Ruta graveolens extract in healing burn infections caused by Staphylococcus aureus and Pseudomonas aeruginosa

Saereh Mohammadpour, Zahra Khodaparast, Hossein Mohammadpour · The Microbe · 2025

Showing 1 of 4 known citations — external sources report more than can currently be individually listed.

Related research

Article metrics

Real usage data collected on this platform.

54

Page views

0

PDF downloads

25

Outbound clicks

4

Citations

Views over time

Views by country

Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".

Traffic sources

Referring site, by host.

Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.