Antibiotic Susceptibility Patterns of Bacterial Isolates from Infected Wounds in a Tertiary Health Care Center, India

Abstract

Background: An infected wound prolongs the period of stay in hospital which results in further chances of getting affected by nosocomial infection leading to increased number of comorbidities. Hence adequate and appropriate treatment of the infective organism is of prime importance. Objectives: To find out the most common antibiotics susceptible to the bacterial isolates from the pus samples.  Materials and Methods: A cross sectional study was conducted of the bacterial isolates from pus samples in a hospital setup of Saveetha medical college and hospital, Chennai for 100 patients. Pus samples were collected from patients who came to the surgery OPD with complaints of ulcer and discharge were subjected to culture and sensitivity after obtaining proper consent and the bacterial growths were noted. Antibiotic susceptibilities of the isolates were determined according to disk diffusion method recommended by the Clinical and Laboratory Standard institute [1]. Results: Out of the total samples collected (n=200) 90% of the samples showed bacterial growth and the remaining 10% of the samples showed no growth. The most predominant bacteria in our study was found to be E. coli (33%) being most susceptible to Amikacin followed by S. aureus (19%) which was highly susceptible to Linezolid and Vancomycin. Conclusion: There is a peak in the incidence of antimicrobial resistant cases which is a great threat for human mankind. Hence emphasis should be laid on rational use of antibiotics and proper sterile techniques to be followed.