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Research Article Open access CC BY 4.0

Antibacterial Activity of Datura metel Linn. (TALONG-PUNAY) Fruit Extract

Karina Milagros C. Lim, Flyndon Mark S. Dagalea, Manuela Cecille G. Vicencio

Journal of Pharmaceutical Research International · pp. 96–101 · Published 5 Sep 2020

10.9734/jpri/2020/v32i2130758

Abstract

Aim: The objective of this study is to determine the phytochemical constituent and antibacterial effect of fruit extract of Datura metel against Staphylococcus aureus and Escherichia coli. Methods: The extract of the sample underwent a phytochemical screening to identify the secondary metabolites present. Also, an antibacterial test was carried out to test its effectiveness, it was tested by impregnating the respective disc on Mueller-Hilton agar streaked with Staphylococcus aureus and Escherichia coli. Results: Datura metel fruit extract was observed to have a good antibacterial activity on the two bacteria and this was due to the presence of the phytochemical compounds terpenoids, saponin, alkaloids, steroid, flavonoids, and tannins. Conclusion: The sample Datura metel fruit extract could be used in the field of pharmaceutical because of its antimicrobial activity and present secondary metabolites.

Antibacterial activity Datura metel Linn phytochemical screening

Cited by 6

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