Anti-inflammatory Activities of the Leaf Chloroform Extract of Palisota hirsuta
Madubuike G. Kelechi, Asuzu I. Uzoma
Journal of Advances in Medical and Pharmaceutical Sciences · pp. 57–63 · Published 6 Dec 2014
10.9734/JAMPS/2015/13813Abstract
Objective: To investigate the anti-inflammatory activity of the chloroform leaf extract of Palisota hirsuta (CLEPH). Methods: CLEPH was evaluated for anti-inflammatory activity using standard experimental models of inflammation namely: Croton oil-induced mouse ear edema, carrageenan-induced rat paw edema and cotton pellet granuloma test. The activities of the extract at different doses were compared to indomethacin, a standard anti-inflammatory drug. Results: In all the experiments, the chloroform extract of P. hirsuta showed in a dose-dependent manner, anti-inflammatory effects which were significant (p˂0.05) and comparable to those of indomethacin. Conclusion: The results showed that CLEPH possess significant anti-inflammatory activity. This supports its use as an anti-inflammatory recipe in folk medicine.
References (11)
- 1 Flavonoids are scavengers of superoxide anions [DOI]
- 2 Small Animal Clinical Pharmacology [DOI]
- 3 Anti-inflammatory, analgesic and antipyretic effects of methanol extract from Bauhinia racemosa stem bark in animal models [DOI]
- 4 Analgesic and Anti-inflammatory Activities of Total Extract and Individual Fractions of Chinese Medicinal Ants Polyrhachis lamellidens [DOI]
- 5 Preliminary studies on anti-inflammatory and analgesic activities of Securinega virosa (Euphorbiaceae) in experimental animal models [DOI]
- 6 Anxiolytic and Antidepressant Effects of a Leaf Extract of Palisota hirsuta K. Schum. (Commelinaceae) in Mice [DOI]
- 7 Anti-Inflammatory Activity ofDelonix regia(Boj. Ex. Hook) [DOI]
- 8 Preliminary Analysis of the Anti-Inflammatory Activity of Essential Oils of Zingiber zerumbet [DOI]
- 9 Anti-Arthritic Effects of Palisota hirsuta K. Schum. Leaf Extract in Freund’s Adjuvant-Induced Arthritis in Rats [DOI]
- 10 Preliminary phytochemical, analgesic and anti-inflammatory studies of the methanol extract of Anisopus mannii (N.E.Br) (Asclepiadaceae) in rodents [DOI]
- 11 Anti-Inflammatory and antipyretic effects of an ethanolic extract of Palisota hirsuta K. Schum roots [DOI]
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