Ano Rectal Plasmablastic Lymphoma in HIV Positive Patient - A Case Report
Temesgen Assefa Ayele, Ephrem Haile Gebreyesus
International Journal of Research and Reports in Hematology · pp. 228–232 · Published 11 Oct 2023
Abstract
Plasmablastic lymphoma (PBL) is an aggressive subtype of non-Hodgkin’s lymphoma (NHL), classified as a distinct entity by the WHO (2008) which frequently arises in the oral cavity of HIV infected patients [1]. It is usually associated with EBV infections, and MYC gene rearrangements [2]. PBL remains a diagnostic and a therapeutic challenge with high rate of relapse and death. There is no standard of care for this entity; current understanding & knowledge of PBL relies primarily on case reports and small case series. We present a case of primary Ano rectal plasmablastic Lymphoma in a 24 years old male HIV positive patient from Ethiopia who presented with a 3 months history rectal bleeding & abdominal pain.
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