Analysis of the Mechanism of Ophiopogon japonicus in Treating Pneumonia Based on Network Pharmacology
Zheng Wang, Peinan Wan, Mingxiu Li, Yi Huang
Journal of Advances in Medical and Pharmaceutical Sciences · pp. 64–74 · Published 18 Jun 2024
10.9734/jamps/2024/v26i6696Abstract
This study explores the mechanism of Ophiopogon japonicus in treating pneumonia through network pharmacology, establishes a physiological and pharmacological relationship between the two based on targets, and emphasizes the interaction between signaling pathways and targets. By utilizing Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis, specific biological processes and signaling pathways are utilized to enhance the understanding of the medicinal properties of traditional Chinese medicine through the use of bioinformatics and biomedical tools. This method aims to identify the key targets and signaling pathways of Ophiopogon japonicus affecting pneumonia status, providing insights into its anti-inflammatory effect in the lungs. The active application of network pharmacology methods in the field of pneumonia is a new trend in the modernization of traditional Chinese medicine.
References (3)
- 1 Network pharmacology to dissect the mechanisms of Yinlai Decoction for pneumonia [DOI]
- 2 Anti-Inflammatory Mechanisms of Total Flavonoids from Mosla scabra against Influenza A Virus-Induced Pneumonia by Integrating Network Pharmacology and Experimental Verification [DOI]
- 3 Anti-Inflammatory and Analgesic Effects and Potential Targets of Shenzhu Jiedu Granule Against Novel Coronavirus Pneumonia Based on Network Pharmacology.
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