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Research Article Open access CC BY 4.0

An Unusual Adrenal Gland Metastasis in a Case of Squamous Cell Carcinoma of Buccal Mucosa

Kazi Sazzad Manir, Sukanta Chakraborty, Satadru Biswas, Debapriya Mondal, Souvik Paul, Chhaya Roy

International Journal of Medical and Pharmaceutical Case Reports · pp. 1–5 · Published 9 Jun 2017

10.9734/IJMPCR/2017/32368

Abstract

The majority of oral cavity cancers presents as localized disease and remain localized until late in the course of their development. Distant metastasis is very rare in carcinoma of buccal mucosa and has a very dismal prognosis. Distant spread is either related to uncontrolled local disease or inadequate local treatment. Lungs and bones are common site for metastases. Extensive metastatic workup should be considered in locally advanced buccal mucosa patients, who either defaulted complete treatment or have an uncontrolled loco-regional relapse. We report a case of unusual adrenal metastasis from Squamous Cell Carcinoma (SCC) of buccal mucosa. 42 years old lady initially presented with cT2N1M0 SCC of buccal mucosa (left) underwent radical surgery followed by post-operative Radiotherapy. After eight months of follow up she developed local relapse. After an initial response to salvage systemic chemotherapy, patient discontinued chemotherapy. After 6 months of discontinuation patient had gradually increasing abdominal pain. Contrast Enhanced Computer Tomography Scan (CECT) showed Left adrenal mass with para-aortic lymph node. Other investigations were normal. CT guided Fine needle Aspiration Cytology (FNAC) showed metastatic deposit of squamous cell origin. Patient is being treated with Tab Gefitinib and supportive medications.

Buccal mucosa squamous cell carcinoma adrenal metastasis

References (5)

  1. 1 Incidence and Sites of Distant Metastases from Head and Neck Cancer [DOI]
  2. 2 Leibel and Phillips textbook of radiation oncology
  3. 3 Distant metastases of a squamous cell carcinoma of the tongue in peripheral skeletal muscles and adjacent soft tissues [DOI]
  4. 4 Carcinoma Buccal Mucosa with Metastasis to Left Adrenal [DOI]
  5. 5 Unusual Distant Metastasis of Oral Cancer to Anterior Abdominal Wall [DOI]

Cited by 2

Primary Adrenal Squamous Cell Carcinoma in a Single Kidney Patient: Case Report and Review of Literature

Mehdi Kardoust Parizi · Prague Medical Report · 2019

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