A Study of Ginseng Effects on Spermatogenesis Multiplications (TDI, RI, SI) Proceeding Scrotal Heat Shock Induction in Rat
Hamed Moradpour, Mehrdad Neshat, Esmaeil Safavi
Journal of Pharmaceutical Research International · pp. 1–7 · Published 18 Jun 2018
10.9734/JPRI/2018/42177Abstract
Objective: Ginseng is a plant which has high Antioxidant feature and contains Ginsenosides that has a high affectivity on testicle’s tissue. This study is done to increase the survival of germ cells and also to find out its effects on decreasing the restoration time of damaged testicle tissues proceeding heat shock induction. Methods and Materials: In this study 60 Vistar rats with the weight of 180-220 g are used which were placed in the same environmental conditions (12 hour light, 12 hour darkness – and temperature of 22±2) and were given the same food. Rats were randomly divided into four groups. Except for the group that was in 23c temperature condition and received the normal amount of Saline, other groups were each divided into three subgroups (ginseng, Vitamin E and 43c). Except for the normal group, all groups were kept for 60 days and went under autopsy in day 15-30-60. Testicles were removed and put into Formalin 10%. After 48-72 hours Lam was made out of samples. Conclusion: In this study effects of Ginseng on testicle tissues which went under heat shock were visible. And the difference in all groups was meaningful and Ginseng had a better function in the restoration of damaged tissues caused by heat than Vitamin E.
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